技術(shù)外包服務(wù):

★脫髓鞘相關(guān)蛋白SH3TC2N抗體費用 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測序、載體構(gòu)建等

★蛋白工程：原核、哺乳動物蛋白表達系統(tǒng)等

★病毒包裝：腺病毒、慢病毒等

★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★細胞工程：細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構(gòu)建、細胞RNAi技術(shù)等等。

實驗流程：

脫髓鞘相關(guān)蛋白SH3TC2N抗體費用 英文名稱  Anti-SH3TC2

中文名稱  脫髓鞘相關(guān)蛋白SH3TC2N抗體費用 

別    名 KIAA1985; CMT4C; D430044G18Rik; FLJ13605; MNMN; PP12494; RGD1309038; S3TC2_HUMAN; SH3 domain and tetratricopeptide repeats-containing protein 2; SH3TC2.

產(chǎn)品屬性：

濃    度  1mg/1ml

規(guī) 格  0.2ml/200μg

抗體來源  Rabbit

克隆類型   polyclonal

交叉反應(yīng)   Human, Mouse, Rat, Pig, Cow, Horse, Rabbit

產(chǎn)品類型   一抗  

研究領(lǐng)域    免疫學(xué) 神經(jīng)生物學(xué)

蛋白分子量  predicted molecular weight: 145kDa 

性    狀   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human SH3TC2

亞    型  IgG

純化方法   affinity purified by Protein A

儲 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

脫髓鞘相關(guān)蛋白SH3TC2N抗體費用 產(chǎn)品應(yīng)用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蠟切片需做抗原修復(fù)） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 SH3TC2 (SH3 domain and tetratricopeptide repeats 2) is a 1,288 amino acid protein that contains one SH3 domain and eight TPR repeats. The SH3TC2 gene encodes a protein expressed in Schwann cells of peripheral nerves, and localized to the plasma membrane and to the perinuclear endocytic recycling compartment, suggesting a possible function in myelination and/or in regions of axoglial interactions. The SH3TC2 protein is expressed in adult heart, testis, spinal cord, and brain as well as in fetal brain and liver. Mild mononeuropathy of the median nerve (MNMN) is caused by heterozygous mutation in the SH3TC2 gene. Also, Charcot-Marie-Tooth disease type 4C (CMT4C) is a more severe neuropathy caused by homozygous or compound heterozygous mutation in the SH3TC2 gene. Existing as four alternatively spliced isoforms and containing 18 exons, the SH3TC2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q32.

Tissue Specificity : Strongly expressed in brain and spinal cord. Expressed at equal level in spinal cord and sciatic nerve. Weakly expressed in striated muscle.

DISEASE : Defects in SH3TC2 are the cause of Charcot-Marie-Tooth disease type 4C (CMT4C) [MIM:601596]. CMT4C is a recessive form of Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathy and primary peripheral axonal neuropathy. Demyelinating CMT neuropathies are characterized by severely reduced nerve conduction velocities (less than 38 m/sec), segmental demyelination and remyelination with onion bulb formations on nerve biopsy, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes, and hollow feet. By convention, autosomal recessive forms of demyelinating Charcot-Marie-Tooth disease are designated CMT4. CMT4C is characterized by onset in childhood, early-onset scoliosis and a distinct Schwann cell pathology.

Similarity : Contains 1 SH3 domain.

Contains 8 TPR repeats.

Database links : UniProtKB/Swiss-Prot: Q8TF17.2

全、新、優(yōu)、品、好四大特點：

脫髓鞘相關(guān)蛋白SH3TC2N抗體費用 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標準品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細胞等，基本上各種科研所需產(chǎn)品在我司都能找到。

新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。

優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。

好：我公司具有優(yōu)質(zhì)的技術(shù)團隊，產(chǎn)品一旦售出，實驗過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。

正在熱銷的相關(guān)產(chǎn)品：

哥倫比亞瓊脂培養(yǎng)基(新藥典)250g用于梭菌的選擇性分離培養(yǎng)

李氏菌選擇性培養(yǎng)基基礎(chǔ)(MMA) 250(g) incubation media 李氏菌選擇性培養(yǎng)基基礎(chǔ)(MMA) 250(g)

溶脲支原體培養(yǎng)基 UU Medium 100毫升 BR

炭疽桿菌噬菌體疽桿菌檢測用配套試劑incubationmedia炭疽桿菌噬菌體疽桿菌檢測用配套試劑

胰酪胨大豆多粘菌素肉湯基礎(chǔ) 250g 用于蠟樣芽孢桿菌選擇性的增菌培養(yǎng)

哥倫比亞瓊脂培養(yǎng)基2406g滅菌后冷至45℃左右時加入5%脫纖維羊血，用于空腸彎曲菌的培養(yǎng)。(CP、GB、EP、USP)

2561-prf TEpiCM-prf 扁桃體上皮細胞培養(yǎng)基 500ml incubation media 2561-prf TEpiCM-prf 扁桃體上皮細胞培養(yǎng)基 500ml

改良馬丁培養(yǎng)基 300ml/袋*10 用于藥品及生物制品霉菌無菌檢驗

Pfizer腸球菌選擇性瓊脂(PSE瓊脂)250g用于糞鏈球菌的選擇性分離和計數(shù)(SN標準)

GCAgar

炭疽桿菌診斷抗原疽桿菌檢測用配套試劑

Membrane-fiter Enterococcus selective agar acc.to SLANETZ and BARTLEY(base) 膜過濾腸球菌選擇瓊脂(基礎(chǔ)) 1.05289.0500 MERCK默克 incubation media Membrane-fiter Enterococcus selective agar acc.to SLANETZ and BARTLEY(base) 膜過濾腸球菌選擇瓊脂(基礎(chǔ)) 1.05289.0500 MERCK默克

硫乙醇酸鹽流體培養(yǎng)基(FT) 250g 用于培養(yǎng)需氧菌、微需氧菌和厭氧菌，還用于藥品生物制品的無菌試驗，及食品中產(chǎn)氣莢膜羧菌的厭氧...

骨髓間質(zhì)干細胞成軟骨誘導(dǎo)分化完全培養(yǎng)基Adultbonemarrowmesenchymalstemcellsintochondrocytesinduceddifferentiationofcompletemedium

SIMpowermedium

CL-0232TF-1(人血液細胞)5×106cells/瓶×2

PTK6 Others Human 人 PTK6 / Brk 桿狀病毒-昆蟲細胞裂解液 (陽性對照)

人平滑肌細胞cDNAHCSMC cDNA

NCL-H460細胞，非小細胞 人肺動脈內(nèi)皮細胞,HPAEC細胞 肝動脈平滑肌細胞Many types of cells包裝：5 × 105次方(1ml)

犬腎細胞;MDCK(NBL-2)

TNFRSF10A Others Human 人 TNFRSF10A / CD261 / APO2 人細胞裂解液 (陽性對照)

脫髓鞘相關(guān)蛋白SH3TC2N抗體費用CL-0231TE-1(人細胞)5×106cells/瓶×2

NRG1 Others Human 人 NRG1-alpha (EGF Domain) 人細胞裂解液 (陽性對照)

小鼠淋巴成纖維細胞完全培養(yǎng)基 100mL

MADB-106大鼠癌細胞 Breast cancer cells of MADB-106 rats 1640+10% FBS

IL1RN Protein Human 重組人 IL-1RA / IL1RN 蛋白 (Fc 標簽)

Psi2 DAP(小鼠胚胎成纖維細胞) 5×106cells/瓶×2 AAV-293( 胚腎細胞)