細胞質(zhì)和紡錘體機化蛋白A抗體規(guī)格 英文名稱  Anti-SPECC1L

中文名稱  細胞質(zhì)和紡錘體機化蛋白A抗體規(guī)格 

別    名 Cytokinesis and spindle organization A; Cytospin-A; CYTSA; CYTSA_HUMAN; Renal carcinoma antigen NY-REN-22; SPECC1-like protein; specc1l; Sperm antigen with calponin homology and coiled-coil domains 1-like.

產(chǎn)品屬性：

濃    度  1mg/1ml

規(guī) 格  0.2ml/200μg

抗體來源  Rabbit

克隆類型   polyclonal

交叉反應(yīng)   Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep

產(chǎn)品類型   一抗  

研究領(lǐng)域    細胞生物 細胞周期蛋白 細胞分化

蛋白分子量  predicted molecular weight: 125kDa 

性    狀   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human SPECC1L

亞    型  IgG

純化方法   affinity purified by Protein A

儲 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

細胞質(zhì)和紡錘體機化蛋白A抗體規(guī)格 產(chǎn)品應(yīng)用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蠟切片需做抗原修復(fù)） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 Involved in cytokinesis and spindle organization.

Function : Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.

Subunit : May interact with both microtubules and actin cytoskeleton.

Subcellular Location : Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cell junction, gap junction. Note=Colocalizes with acetylated alpha-tubulin, gamma-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center.

DISEASE : Defects in SPECC1L are the cause of facial clefting oblique type 1 (OBLFC1) [MIM:600251]. A rare form of facial clefting. A facial cleft is any of the fissures between the embryonic prominences that normally unite to form the face.

Similarity : Belongs to the cytospin-A family.

Contains 1 CH (calponin-homology) domain.

Database links : UniProtKB/Swiss-Prot: Q69YQ0.2

實驗流程：

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