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鈉通道蛋白11α抗體品牌
  • 品牌:上海莼試
  • 產(chǎn)地:進口、國產(chǎn)
  • 貨號:CS12179
  • 發(fā)布日期: 2019-02-18
  • 更新日期: 2025-03-14
產(chǎn)品詳請
產(chǎn)地 進口、國產(chǎn)
品牌 上海莼試
保存條件 Store at -20 °C
貨號 CS12179
應用范圍 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
CAS編號
抗體名 Anti-SCN11A/NAV1.9
克隆性
靶點 詳見說明書
適應物種 詳見說明書
形態(tài) 詳見說明書
宿主 詳見說明書
亞型 IgG
標識物 詳見說明書
濃度 1mg/1ml%
免疫原 KLH conjugated synthetic peptide derived from human SCN11A/NAV1.9 (656-705aa)

全、新、優(yōu)、品、好四大特點:

鈉通道蛋白11α抗體品牌 全:公司提供上萬種產(chǎn)品,涵蓋了生物試劑,elisa試劑盒,標準品,培養(yǎng)基,原裝耗材,抗體、培養(yǎng)基、ATCC細胞等,基本上各種科研所需產(chǎn)品在我司都能找到。

新:產(chǎn)品更新速度較快,基本上每周都有新產(chǎn)品出現(xiàn)。

優(yōu):產(chǎn)品質量好,投訴比較少。

好:我公司具有優(yōu)質的技術團隊,產(chǎn)品一旦售出,實驗過程中遇到困難可提供在線技術咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。

鈉通道蛋白11α抗體品牌 英文名稱  Anti-SCN11A/NAV1.9

中文名稱  鈉通道蛋白11α抗體品牌 

     hNaN; NaN; NAV1.9; Peripheral nerve sodium channel 5; PN 5; PN5; SCN 11A; SCN 12A; SCN12A; Sensory neuron sodium channel 2; SNS 2; SNS2; Sodium channel protein type 11 subunit alpha; Sodium channel protein type XI subunit alpha; Sodium channel voltage gated type XI alpha; Sodium channel voltage gated type XI alpha polypeptide; Sodium channel voltage gated type XI alpha subunit; Sodium channel voltage gated type XII alpha polypeptide; Voltage gated sodium channel Nav1.9; Voltage gated sodium channel subunit alpha Nav1.9.

產(chǎn)品屬性:

      1mg/1ml

規(guī)   0.2ml/200μg

抗體來源  Rabbit

克隆類型   polyclonal

交叉反應   Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit

產(chǎn)品類型   一抗  

研究領域    神經(jīng)生物學 通道蛋白 細胞膜受體

蛋白分子量  predicted molecular weight: 197kDa 

       Lyophilized or Liquid

  KLH conjugated synthetic peptide derived from human SCN11A/NAV1.9 (656-705aa)

      IgG

純化方法   affinity purified by Protein A

   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

鈉通道蛋白11α抗體品牌 產(chǎn)品應用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

(石蠟切片需做抗原修復) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 Voltage gated sodium channels are membrane protein complexes that play a fundamental role in generating and transmitting action potentials in neuronal cells. SCN11A (Sodium channel, voltage gated, type XI, alpha subunit) mediates the voltage dependent sodium ion permeability and conductance. It forms the pore of the sodium selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin resistant sodium channel isoform.

Function : This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization.

Subunit : he voltage-resistant sodium channel consists of an ion conducting pore forming alpha-subunit regulated by one or more auxiliary subunits SCN1B, SCN2B and SCN3B.

Subcellular Location : Membrane; Multi-pass membrane protein.

Tissue Specificity : Expressed in the dorsal root ganglia and trigeminal ganglia, olfactory bulb, hippocampus, cerebellar cortex, spinal cord, spleen, small intestine and placenta.

Similarity : Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.9/SCN11A subfamily.

實驗流程:

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技術外包服務:

鈉通道蛋白11α抗體品牌 分子生物學:質粒抽提、PCRQ-PCR、RT-PCR、分子生物學:基因合成、引物合成、基因測序、載體構建等

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病毒包裝:腺病毒、慢病毒等

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細胞工程:細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構建、細胞RNAi技術等等。

 


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