全、新、優(yōu)、品、好四大特點(diǎn)：

同源轉(zhuǎn)錄調(diào)節(jié)蛋白Sin3A抗體說明書 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標(biāo)準(zhǔn)品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細(xì)胞等，基本上各種科研所需產(chǎn)品在我司都能找到。

新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。

優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。

好：我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊(duì)，產(chǎn)品一旦售出，實(shí)驗(yàn)過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時(shí)沒有任何的后顧之憂。

同源轉(zhuǎn)錄調(diào)節(jié)蛋白Sin3A抗體說明書 英文名稱  Anti-mSin3A

中文名稱  同源轉(zhuǎn)錄調(diào)節(jié)蛋白Sin3A抗體說明書 

別    名 Histone deacetylase complex subunit Sin 3a; Histone deacetylase complex subunit Sin3a; Paired amphipathic helix protein Sin 3a; Paired amphipathic helix protein Sin3a; Sin 3a; SIN3 homolog A; SIN3 homolog A transcription regulator (yeast); SIN3 homolog A transcription regulator; Sin3a; SIN3A protein; Transcriptional co repressor Sin 3A; Transcriptional co repressor Sin3A; Transcriptional regulator SIN3A; SIN3A_MOUSE.

產(chǎn)品屬性：

濃    度  1mg/1ml

規(guī) 格  0.2ml/200μg

抗體來源  Rabbit

克隆類型   polyclonal

交叉反應(yīng)   Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep

產(chǎn)品類型   一抗  

研究領(lǐng)域     細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)

蛋白分子量  predicted molecular weight: 145kDa 

性    狀   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from mouse Sin3A

亞    型  IgG

純化方法   affinity purified by Protein A

儲(chǔ) 存 液   0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

同源轉(zhuǎn)錄調(diào)節(jié)蛋白Sin3A抗體說明書 產(chǎn)品應(yīng)用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蠟切片需做抗原修復(fù)） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 Mammalian Sin 3 (mSin 3) is a protein closely related to the yeast SIN3 repressor protein involved in the transcriptional repression of many genes. There are two mammalian isoforms, mSin 3A and mSin 3B. Containing 4 paired amphipathic helix domains (PAH domains), mSin 3A and mSin 3B have been shown to directly interact with several other transcriptional repressor proteins including HDAC 1, HDAC 2, RbAp 46, the methyl CpG binding protein MeCP 2, the Mad/Max heterodimer, and the corepressors silencing mediator of retinoic acid & thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR).

Function : Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation.

Subunit : Interacts with ARID4B, BRMS1L, HCFC1, HDAC1, HDAC2, MXI1, SAP30L, SAP130, SFPQ and TOPORS. Interacts with OGT (via TPRs 1-6); the interaction mediates transcriptional repression in parallel with histone deacetylase (By similarity). Interacts with BAZ2A, MXD3, MXD4, MBD2, DACH1, NCOR1, NR4A2, REST, RLIM, SAP30, SETDB1, SMYD2, and SUDS3. Interacts with PHF12 in a complex composed of HDAC1, PHF12 and SAP30. Interacts with TET1; the interaction recruits SIN3A to gene promoters.

Subcellular Location : Nucleus. Nucleus, nucleolus. Note=Recruited to the nucleolus by SAP30L (By similarity).

Tissue Specificity : Widely expressed. Highest levels in testis, lung and thymus.

Post-translational modifications : SUMO1 sumoylated by TOPORS. Probably desumoylated by SENP2 (By similarity).

Similarity : Contains 3 PAH (paired amphipathic helix) domains.

Database links : UniProtKB/Swiss-Prot: Q60520.3

實(shí)驗(yàn)流程：

正在熱銷的相關(guān)產(chǎn)品：

3-羰基-5-α類固醇4脫氫酶1 多克隆抗體  S5A1 Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

3-羰基-5-α類固醇4脫氫酶2 多克隆抗體  S5A2 Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

溶質(zhì)載體家族6成員12 多克隆抗體  S6A12 Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

溶質(zhì)載體家族6成員13 多克隆抗體  S6A13 Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

溶質(zhì)載體家族6成員18 多克隆抗體  S6A18 Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

酰基輔酶A脫氫酶中鏈抗體     轉(zhuǎn)錄增強(qiáng)因子TEF4抗體

?；o酶A脫氫酶短鏈抗體     轉(zhuǎn)錄增強(qiáng)因子TEF3抗體

過氧化物酶?；o酶A氧化酶1抗體     轉(zhuǎn)錄因子相關(guān)蛋白NKX6.1抗體

磷酸化細(xì)胞凋亡信號(hào)調(diào)節(jié)激酶1抗體     轉(zhuǎn)錄因子THOC2抗體

轉(zhuǎn)化生長(zhǎng)因子β誘導(dǎo)蛋白3抗體（半胱氨酸和絲氨酸富含核蛋白1）     轉(zhuǎn)錄因子TBX6抗體

轉(zhuǎn)運(yùn)蛋白SEC61B 多克隆抗體  SC61B Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

內(nèi)質(zhì)網(wǎng)蛋白SC65 多克隆抗體  SC65 Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

溶質(zhì)載體家族6成員3 多克隆抗體  SC6A3 Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

溶質(zhì)載體家族6成員4 多克隆抗體  SC6A4 Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

溶質(zhì)載體家族6成員7 多克隆抗體  SC6A7 Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

重樓Paris yunnanensis Franch. Polyphyllin III 重樓皂苷III 19057-60-4 C45H72O16 ≥98%

牡荊速葡萄糖苷VitqxinglucosidqHPLC≥98%;20mg/支

燈盞花甲素;芹菜素-7-O-葡萄糖全酸苷 Apigenin-7-O-glucronide 29741-09-1 20mg HPLC≥98% 燈盞花甲素 29741-09-1

中藥對(duì)照藥材菊苣(毛菊苣)121388-200401TLC法鑒別

Escin IA;Aescin IA

同源轉(zhuǎn)錄調(diào)節(jié)蛋白Sin3A抗體說明書相思子 Abrin 5g

澤瀉隊(duì)照藥材Rhizomaalismatisconolmedicine1g

3-Acetoxy-5-metxoxystilbene (E)-3-ACETOXY-5-metxOXYSTILBENE 71144-78-0

貝母辛19773-24-1Peimisine

異綠原酸A;Isochlorogenic 2450-53-5 20mg 訂購(gòu)|咨詢

技術(shù)外包服務(wù):

★同源轉(zhuǎn)錄調(diào)節(jié)蛋白Sin3A抗體說明書 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測(cè)序、載體構(gòu)建等

★蛋白工程：原核、哺乳動(dòng)物蛋白表達(dá)系統(tǒng)等

★病毒包裝：腺病毒、慢病毒等

★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★細(xì)胞工程：細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。