![]() |
產(chǎn)地 | 進口、國產(chǎn) |
品牌 | 上海莼試 |
保存條件 | Store at -20 °C |
貨號 | CS11792 |
應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 |
CAS編號 | |
抗體名 | Anti-TRIM5α/RNF88 |
克隆性 | |
靶點 | 詳見說明書 |
適應(yīng)物種 | 詳見說明書 |
形態(tài) | 詳見說明書 |
宿主 | 詳見說明書 |
亞型 | IgG |
標識物 | 詳見說明書 |
濃度 | 1mg/1ml% |
免疫原 | KLH conjugated synthetic peptide derived from human TRIM5α/RNF88 corresponding to amino acids 351-450. |
環(huán)指蛋白88抗體說明書 英文名稱 Anti-TRIM5α/RNF88
中文名稱 環(huán)指蛋白88抗體說明書
別 名 TRIM5 alpha; RING finger protein 88; RNF88; TRIM5; TRIM5_HUMAN; tripartite motif protein 5; tripartite motif protein TRIM5; Tripartite motif-containing protein 5.
產(chǎn)品屬性:
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human
產(chǎn)品類型 一抗
研究領(lǐng)域 細胞生物 免疫學(xué) 表觀遺傳學(xué)
蛋白分子量 predicted molecular weight: 54kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM5α/RNF88 corresponding to amino acids 351-450.
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
環(huán)指蛋白88抗體說明書 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
(石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 TRIM5a is a 493 amino acid member of the large tripartite motif protein (TRIM) family. TRIM proteins are composed of three zinc-binding domains, a RING, a B-box 2 and a coiled-coil domain, and they use homomultimerization to identify different cell compartments. Some TRIM proteins, such as TRIM5? also possess a carboxy-terminal B30.2 (SPRY) domain and localize to the cytoplasm. TRIM5?mediates innate intracellular retroviral resistance, which is dependent on its carboxy-terminal domain. The three variable regions of the B30.2 domain form loops on one side of the B30.2 core structure of TRIM5?which may form a binding surface for the virus. TRIM5?trimerization plays a major role in its affinity for the retroviral capsid, and in its ability to inhibit virus infection. The linker region between the coiled-coil and B30.2 domains of TRIM5?is required for this trimerization. TRIM5?blocks infection after the virus has entered the cell.
Subunit : Isoform Alpha forms homotrimers, and may interact with retroviral CA protein. Isoform Delta interacts with BTBD1 and BTBD2.
Subcellular Location : Cytoplasm, P-body.
Similarity : Belongs to the TRIM/RBCC family.
Contains 1 B box-type zinc finger.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.
科學(xué)家經(jīng)過研究發(fā)現(xiàn)TRIM5蛋白有阻止HIV繁殖的作用,在毒感染過程中,一旦HIV進入細胞,TRIM5蛋白立刻攔截并阻止其繁殖。因此, TRIM5是先天中對HIV的感應(yīng)器。與適應(yīng)性“后發(fā)制人”不同,先天能夠在接觸到病原體時立刻將其消除。
實驗流程:
全、新、優(yōu)、品、好四大特點:
環(huán)指蛋白88抗體說明書 全:公司提供上萬種產(chǎn)品,涵蓋了生物試劑,elisa試劑盒,標準品,培養(yǎng)基,原裝耗材,抗體、培養(yǎng)基、ATCC細胞等,基本上各種科研所需產(chǎn)品在我司都能找到。
新:產(chǎn)品更新速度較快,基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu):產(chǎn)品質(zhì)量好,投訴比較少。
好:我公司具有優(yōu)質(zhì)的技術(shù)團隊,產(chǎn)品一旦售出,實驗過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。
正在熱銷的相關(guān)產(chǎn)品:
Anti-Profilin 2/FITC 熒光素標記前纖維蛋白2抗體IgGMulti-class antibodies規(guī)格: 0.2ml
Rabbit Anti-human k-chain Whole serum 兔抗人k-鏈抗血清Multi-class antibodies規(guī)格: 1ml
白介素受體相關(guān)蛋白樣1前體蛋白抗體 Anti-IL1RAPL1 0.2ml
Rabbit anti-mouse IgG whole serum 兔抗小鼠IgG抗血清 1ml
FCGRT 英文名稱: IgG-Fc片斷受體轉(zhuǎn)運蛋白α抗體 0.1ml
Rhesus antibody Rh phospho-PTK9/TWF1(Ty*1) 磷酸化蛋白酪氨酸激酶9抗體 規(guī)格 0.1ml
Rabbit Anti-human k-chain Whole serum 兔抗人k-鏈抗血清Multi-class antibodies規(guī)格: 1ml
LPLUNC1 人癌基因多肽抗原Multi-class antibodies規(guī)格: 0.5mg
Anti-ALR 肝再生增強因子抗體Multi-class antibodies規(guī)格: 0.2ml
Rhesus antibody Rh phospho-c-Abl(Thr754) 磷酸化非受體酪氨酸激酶c-Abl抗體 規(guī)格 0.1ml
鏈酶蛋白酶濃縮液(20X) 1ml 1% pH 7.2
Vinexin 英文名稱: 細胞間粘附蛋白Vinexin抗體 0.1ml
phospho-DAAM1 (Thr361) 英文名稱: 磷酸化形態(tài)發(fā)生紊亂關(guān)聯(lián)激活因子1抗體 0.1ml
Anti-ALR 肝再生增強因子抗體Multi-class antibodies規(guī)格: 0.2ml
Anti- Alpha-AF/ Alpha-Afa/FITC 熒光素標記α-L-阿拉伯糖苷酶抗體IgGMulti-class antibodies規(guī)格: 0.2ml
DR5/TNFRSF10B/CD262 (Death receptor 5) 細胞調(diào)亡素/死亡受體5抗原Multi-class antibodies規(guī)格: 0.5mg
N-甲基嘌呤DNA糖基化酶 Anti-APNG/MPG 0.1ml
ZSWIM2 英文名稱: E3泛素蛋白連接酶ZSWIM2抗體 0.2ml
DUSP7 英文名稱: 雙特異性蛋酸酶7抗體 0.2ml
Rhesus antibody Rh phospho-Eph receptor A2+A3+A4 (Tyr588 + Tyr596) 磷酸化內(nèi)皮細胞受體蛋白酪氨酸激酶A2+A3+A4抗體 規(guī)格 0.1ml
DR5/TNFRSF10B/CD262 (Death receptor 5) 細胞調(diào)亡素/死亡受體5抗原Multi-class antibodies規(guī)格: 0.5mg
人β2糖蛋白(β2-GP)ELISA 試劑盒 96T/48T 試劑盒 組裝/原裝
兔子促甲狀腺素(TSH)免疫試劑盒 Rabbit Thyroid Stimulating Hormone,TSH ELISA Kit
乳酸脫氫酶(LDH)ELISA試劑盒 ,英文名: LDH ELISA Kit
PorcinesolubleE-selectin,sE-selectinELISA試劑盒豬可溶性E選擇素(sE-selectin)ELISA試劑盒規(guī)格:96T/48T
Humanangiotensinogen,aGTELISA試劑盒人緊張素原(aGT)ELISA試劑盒規(guī)格:96T/48T
HumanBcellactivationfactorrfromthetumornecrosisfactorfamilyreceptor,BAFF-RELISAKit人B細胞活化因子受體(BAFF-R)ELISA試劑盒規(guī)格:96T/48T
大鼠生長停滯DNA損傷可誘導(dǎo)蛋白α(GADD45α)ELISA試劑盒 ,英文名: GADD45α ELISA Kit
Chicken ierferon gamma (IFN- gamma) ELISA Kit 雞γ干擾素(IFN-γ)ELISA試劑盒
Rat17-Hydroxycoicosteroids,17-OHCSELISAKit 大鼠17羥皮質(zhì)類固醇(17-OHCS)ELISA試劑盒 96T/48T 進口分裝
CLIAKitforHD(HumanHistoneDeacetylase)ELISAKit人組織蛋白去乙酰化酶規(guī)格:48T/96T
細胞TUNEL熒光法(Fluorescein)測定試劑盒10次
ELISAKiCA蓖麻凝集素規(guī)格:48T/96T
環(huán)指蛋白88抗體說明書 大鼠脫氫表雄酮(DHEA)ELISA試劑盒 ,英文名: DHEA ELISA Kit
人癌標志物-CA153ELISA檢測試劑盒HumanmammarycarcinomaMarker-CA153ELISAKit 96T/48T
倉鼠谷胱甘肽過氧化物酶3(GPX3)免疫試劑盒 Hamster glathione peroxidase 3,GPX3 ELISA kit
CLIAKitforPV-IgG(HumanPoliomyelitisVirus)ELISAKit人病毒IgG規(guī)格:48T/96T
石蠟切片脂質(zhì)尼羅紅間接染色試劑盒50次
ELISAKitOPG人骨保護素規(guī)格:48T/96T
技術(shù)外包服務(wù):
★環(huán)指蛋白88抗體說明書 分子生物學(xué):質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué):基因合成、引物合成、基因測序、載體構(gòu)建等
★蛋白工程:原核、哺乳動物蛋白表達系統(tǒng)等
★病毒包裝:腺病毒、慢病毒等
★抗體工程:磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細胞工程:細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構(gòu)建、細胞RNAi技術(shù)等等。