T細胞急性淋巴母細胞相關(guān)抗原1抗體說明書 英文名稱  Anti-TALLA-1/CD231

中文名稱  T細胞急性淋巴母細胞相關(guān)抗原1抗體說明書 

別    名 CD231 antigen; Cell surface glycoprotein A15; Membrane component X chromosome surface marker 1; T cell acute lymphoblastic leukemia associated antigen 1; TALLA 1; TALLA1; Tetraspanin 7; Tetraspanin-7; Transmembrane 4 superfamily member 2; Tspan 7; TSN7_HUMAN; Tspan-7; TALLA-1.

產(chǎn)品屬性：

濃    度  1mg/1ml

規(guī) 格  0.2ml/200μg

抗體來源  Rabbit

克隆類型   polyclonal

交叉反應(yīng)   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep

產(chǎn)品類型   一抗  

研究領(lǐng)域     細胞生物 信號轉(zhuǎn)導(dǎo) 細胞表面分子

蛋白分子量  predicted molecular weight: 28kDa 

性    狀   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human Tetraspanin-7

亞    型  IgG

純化方法   affinity purified by Protein A

儲 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

T細胞急性淋巴母細胞相關(guān)抗原1抗體說明書 產(chǎn)品應(yīng)用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-100 IF=1:50-200

（石蠟切片需做抗原修復(fù)） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 Tetraspanins are a group of hydrophobic membrane proteins that interact with a wide variety of proteins including intracellular signaling molecules, integrins and membrane receptors. TSPAN7 (tetraspanin 7), also known as MXS1 (membrane component chromosome X surface marker 1) or TM4SF2 (transmembrane 4 superfamily member 2), is a 249 amino acid multi-pass membrane protein belonging to the tetraspanin (TM4SF) family of transmembrane proteins. TSPAN7 is believed to play a role in cell motility and cell proliferation. The gene that encodes TSPAN7 maps to human chromosome X and defects in this gene are a cause of mental retardation X-linked type 58 (MRX58), which is characterized by dramatically below average general intellectual functioning.

Function : May be involved in cell proliferation and cell motility.

Subunit : Interacts with herpes simplex virus 1 (HHV-1) UL35.

Subcellular Location : Membrane; Multi-pass membrane protein.

Tissue Specificity : Not solely expressed in T-cells. Expressed in acute myelocytic leukemia cells of some patients.

DISEASE : Defects in TSPAN7 are the cause of mental retardation X-linked type 58 (MRX58) [MIM:300210]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.

Similarity : Belongs to the tetraspanin (TM4SF) family.

Database links : UniProtKB/Swiss-Prot: P41732.2

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