上海莼試生物技術(shù)有限公司
   
菜單 Close 公司首頁 公司介紹 公司動(dòng)態(tài) 產(chǎn)品展廳 證書榮譽(yù) 聯(lián)系方式 在線留言
您當(dāng)前的位置: 網(wǎng)站首頁 > 產(chǎn)品展廳 >抗體 >瞬時(shí)受體電位離子通道蛋白4抗體(M亞家族)品牌
產(chǎn)品展廳
瞬時(shí)受體電位離子通道蛋白4抗體(M亞家族)品牌
  • 品牌:上海莼試
  • 產(chǎn)地:進(jìn)口、國產(chǎn)
  • 貨號(hào):CS11663
  • 發(fā)布日期: 2019-01-21
  • 更新日期: 2025-03-18
產(chǎn)品詳請(qǐng)
產(chǎn)地 進(jìn)口、國產(chǎn)
品牌 上海莼試
保存條件 Store at -20 °C
貨號(hào) CS11663
應(yīng)用范圍 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
CAS編號(hào)
抗體名 Anti-TRPM4
克隆性
靶點(diǎn) 詳見說明書
適應(yīng)物種 詳見說明書
形態(tài) 詳見說明書
宿主 詳見說明書
亞型 IgG
標(biāo)識(shí)物 詳見說明書
濃度 1mg/1ml%
免疫原 KLH conjugated synthetic peptide derived from human TRPM4

全、新、優(yōu)、品、好四大特點(diǎn):

瞬時(shí)受體電位離子通道蛋白4抗體(M亞家族)品牌 全:公司提供上萬種產(chǎn)品,涵蓋了生物試劑,elisa試劑盒,標(biāo)準(zhǔn)品,培養(yǎng)基,原裝耗材,抗體、培養(yǎng)基、ATCC細(xì)胞等,基本上各種科研所需產(chǎn)品在我司都能找到。

新:產(chǎn)品更新速度較快,基本上每周都有新產(chǎn)品出現(xiàn)。

優(yōu):產(chǎn)品質(zhì)量好,投訴比較少。

好:我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊(duì),產(chǎn)品一旦售出,實(shí)驗(yàn)過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時(shí)沒有任何的后顧之憂。

瞬時(shí)受體電位離子通道蛋白4抗體(M亞家族)品牌 英文名稱  Anti-TRPM4

中文名稱  瞬時(shí)受體電位離子通道蛋白4抗體(M亞家族)品牌 

     Long transient receptor potential channel 4; LTrpC-4; LTrpC4; Melastatin 4; Melastatin like 2 protein; Melastatin-4; Melastatin-like 2; Mls2s; PFHB1B; Transient receptor potential cation channel subfamily M member 4; Transient receptor potential cation channel, subfamily M, member 4; Trpm4; TRPM4_HUMAN; TRPM4B; 1110030C19Rik; AW047689; Calcium-activated non-selective cation channel 1; FLJ20041; hTRPM4.

產(chǎn)品屬性:

      1mg/1ml

規(guī)   0.2ml/200μg

抗體來源  Rabbit

克隆類型   polyclonal

交叉反應(yīng)   Human, Mouse, Rat

產(chǎn)品類型   一抗  

研究領(lǐng)域    細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 通道蛋白

蛋白分子量  predicted molecular weight: 134kDa 

       Lyophilized or Liquid

  KLH conjugated synthetic peptide derived from human TRPM4

      IgG

純化方法   affinity purified by Protein A

儲(chǔ)    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

瞬時(shí)受體電位離子通道蛋白4抗體(M亞家族)品牌 產(chǎn)品應(yīng)用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

(石蠟切片需做抗原修復(fù)) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.

Involvement in disease:

Defects in TRPM4 are the cause of progressive familial heart block type 1B (PFHB1B) [MIM:604559]. It is a cardiac bundle branch disorder characterized by progressive alteration of cardiac conduction through the His-Purkinje system, with a pattern of a right bundle-branch block and/or left anterior hemiblock occurring individually or together. It leads to complete atrio-ventricular block causing syncope and sudden death.

Function : Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.

Subunit : Homomultimer.

Subcellular Location : Endoplasmic reticulum. Golgi apparatus and Cell membrane. Endoplasmic reticulum. Golgi apparatus

Tissue Specificity : Widely expressed with a high expression in intestine and prostate. In brain, it is both expressed in whole cerebral arteries and isolated vascular smooth muscle cells. Prominently expressed in Purkinje fibers. Expressed at higher levels in T-helper 2 (Th2) cells as compared to T-helper 1 (Th1) cells.

Post-translational modifications : Phosphorylation by PKC leads to increase the sensitivity to Ca(2+).

Sumoylated. Desumoylated by SENP1.

DISEASE : Defects in TRPM4 are the cause of progressive familial heart block type 1B (PFHB1B) [MIM:604559]. It is a cardiac bundle branch disorder characterized by progressive alteration of cardiac conduction through the His-Purkinje system, with a pattern of a right bundle-branch block and/or left anterior hemiblock occurring individually or together. It leads to complete atrioventricular block causing syncope and sudden death.

Similarity : Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM4 sub-subfamily.

Database links :

Entrez Gene: 54795 Human

Entrez Gene: 68667 Mouse

Entrez Gene: 171143 Rat

Omim: 606936 Human

SwissProt: Q8TD43 Human

SwissProt: Q7TN37 Mouse

SwissProt: Q9ESQ5 Rat

Unigene: 467101 Human

Unigene: 439890 Mouse

Unigene: 205004 Rat

實(shí)驗(yàn)流程:

正在熱銷的相關(guān)產(chǎn)品:

Anti-TSHR(CT)/FITC 熒光素標(biāo)記促甲狀腺素受體抗體(C端)IgGMulti-class antibodies規(guī)格: 0.2ml

TmR2(GDNFR Beta;TRN-R;GFR-alpha-2;NTNR-2) 膠質(zhì)細(xì)胞系源性神經(jīng)營養(yǎng)因子(多肽)Multi-class antibodies規(guī)格: 0.5mg

卵黃蛋白原抗體 Anti-VTG 0.2ml

Phospho-MEK4 (Ser257) 英文名稱: 磷酸化原活化蛋白激酶激酶4抗體 0.1ml

LPA3 英文名稱: 溶血磷脂酸受體蛋白3抗體 0.2ml

Rhesus antibody Rh phospho-IKK beta(Tyr188) 磷酸化KB抑制蛋白激酶β抗體 規(guī)格 0.1ml

TmR2(GDNFR Beta;TRN-R;GFR-alpha-2;NTNR-2) 膠質(zhì)細(xì)胞系源性神經(jīng)營養(yǎng)因子(多肽)Multi-class antibodies規(guī)格: 0.5mg

GLUT3(Glucose transporter 3) 葡萄糖轉(zhuǎn)運(yùn)蛋白3抗原Multi-class antibodies規(guī)格: 0.5mg

L1CAM CD171 / N-CAML1 / L1CAM 鼠單抗 (PE) Human

Rhesus antibody Rh Phospho-Cyclin B1(Ser133) 磷酸化周期素B1抗體 規(guī)格 0.1ml

Western轉(zhuǎn)膜液 1L 自產(chǎn)

Zic2 英文名稱: 鋅指蛋白Zic2抗體 0.2ml

DAZ1 英文名稱: 缺失基因1抗體 0.2ml

L1CAM CD171 / N-CAML1 / L1CAM 鼠單抗 (PE) Human

Mouse Beta-Defensins, Beta-DF ELISA Kit 小鼠β-防御素Multi-class antibodies規(guī)格: 48T

Anti-AQP-2/HRP (aquaporin Protein-2) 辣根過氧化物酶標(biāo)記水通道蛋白-2抗體IgGMulti-class antibodies規(guī)格: 0.2ml

Rhesus antibody Rh ERAS/HRAS2 胚胎干細(xì)胞RAS蛋白抗體 規(guī)格 0.2ml

Mouse Beta-catenin, Beta-cat ELISA Kit 小鼠β連環(huán)蛋白/聯(lián)蛋白 96T

beta 2 Microglobulin 英文名稱: β2微球蛋白抗體 0.1ml

APOJ 英文名稱: 載脂蛋白J抗體 0.1ml

Anti-AQP-2/HRP (aquaporin Protein-2) 辣根過氧化物酶標(biāo)記水通道蛋白-2抗體IgGMulti-class antibodies規(guī)格: 0.2ml

人保護(hù)素(CD59)ELISA試劑盒 96T/48T 試劑盒 組裝/原裝

兔子粘蛋白1(MUC1)免疫試劑盒 Rabbit Mucin 1,MUC1 ELISA Kit

水通道蛋白4(AQP-4)ELISA試劑盒 ,英文名: AQP-4 ELISA Kit

Placalmodulin,CAMELISA試劑盒植物鈣調(diào)素(CAM)ELISA試劑盒規(guī)格:96T/48T

guineapigiestinalfattyacidbindingprotein,iFABPELISA試劑盒豚鼠腸脂肪酸結(jié)合蛋白(iFABP)ELISA試劑盒規(guī)格:96T/48T

Humanai-Endostatinaibody,ES-AbELISAKit人內(nèi)皮抑素抗體(ES-Ab)ELISA試劑盒規(guī)格:96T/48T

大鼠糖原合成酶激酶(GSK)ELISA 試劑盒 96T/48T 試劑盒 組裝/原裝

人唾液酸酶免疫試劑盒 Human Sialidase ELISA Kit

植物組織果糖含量測(cè)試盒 可見分光光度法 50管/48樣

RatsecretoryimmunoglobulinA,sIgAELISA試劑盒大鼠分泌型免疫球蛋白A(sIgA)ELISA試劑盒規(guī)格:96T/48T

HumanIerleukin23,IL-23ELISA試劑盒人白介素23(IL-23)ELISA試劑盒規(guī)格:96T/48T

HumanMycoplasmapneumoniaeaibody,MP-AbELISAKit人支原體抗體(MP-Ab)ELISAKi規(guī)格:96T/48T

瞬時(shí)受體電位離子通道蛋白4抗體(M亞家族)品牌 大鼠細(xì)胞周期素D1(CCND1)ELISA試劑盒 ,英文名: CCND1 ELISA Kit

Mouse three iodothyronine (T3) ELISA Kit 小鼠三甲狀腺原氨酸(T3)ELISA試劑盒

MouseSolubleprotein-100,S-100ELISAKit 小鼠S100蛋白(S-100)ELISA試劑盒 96T/48T 進(jìn)口分裝

CLIAKitforHSVII-Ab(HumanHerpessimplexvirusIIaibody)ELISAKit人單純病毒Ⅱ型抗體規(guī)格:48T/96T

細(xì)胞IKKβ激酶活性定量檢測(cè)試劑盒(A/B/C)20次

ELISAKitLTE4大鼠白三烯E4規(guī)格:48T/96T

技術(shù)外包服務(wù):

瞬時(shí)受體電位離子通道蛋白4抗體(M亞家族)品牌 分子生物學(xué):質(zhì)粒抽提、PCR、Q-PCRRT-PCR、分子生物學(xué):基因合成、引物合成、基因測(cè)序、載體構(gòu)建等

蛋白工程:原核、哺乳動(dòng)物蛋白表達(dá)系統(tǒng)等

病毒包裝:腺病毒、慢病毒等

抗體工程:磁珠分選、病理染色、WB、ELISA、IPIF、IHC、FACSConfocal等等

細(xì)胞工程:細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。


聯(lián)系方式
手機(jī):13585831301
Q Q:
亚洲精品乱码久久久久久久久久久久,国产精品视频色尤物yw,亚洲AV日韩AV永久无码色欲,亚洲a∨精品永久无码