技術(shù)外包服務(wù):

★瞬時受體電位蛋白12抗體規(guī)格 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測序、載體構(gòu)建等

★蛋白工程：原核、哺乳動物蛋白表達系統(tǒng)等

★病毒包裝：腺病毒、慢病毒等

★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★細胞工程：細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構(gòu)建、細胞RNAi技術(shù)等等。

實驗流程：

瞬時受體電位蛋白12抗體規(guī)格 英文名稱  Anti-TRPV4/TRP12

中文名稱  瞬時受體電位蛋白12抗體規(guī)格 

別    名 osm-9-like TRP channel 4; OTRPC 4; OTRPC4; Transient receptor potential cation channel subfamily V member 4; Transient receptor potential protein 12; TRP 12; TRP12; TRPV 4; Vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; Vanilloid receptor-related osmotically-activated channel; VR 4; VR OAC; VR4; VRL 2; VRL2; VROAC.

產(chǎn)品屬性：

濃    度  1mg/1ml

規(guī) 格  0.2ml/200μg

抗體來源  Rabbit

克隆類型   polyclonal

交叉反應(yīng)   Human, Mouse, Rat, Chicken, Dog, Pig, Cow

產(chǎn)品類型   一抗  

研究領(lǐng)域     細胞生物 免疫學(xué) 微生物學(xué) 信號轉(zhuǎn)導(dǎo) 通道蛋白 表觀遺傳學(xué)

蛋白分子量  predicted molecular weight: 96kDa 

性    狀   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human TRPV4

亞    型  IgG

純化方法   affinity purified by Protein A

儲 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

瞬時受體電位蛋白12抗體規(guī)格 產(chǎn)品應(yīng)用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蠟切片需做抗原修復(fù)） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 The detection of noxious stimuli (chemical, mechanical, or thermal) occurs predominantly at the peripheral terminals of primary afferent neurons. This information is ultimately transmitted to the central nervous system to evoke appropriate protective reflexes. TRPV4 is a non selective calcium permeant, swell activated, cation channel probably involved in osmotic and mechano sensitivity. Activation by exposure to hypotonicity within the physiological range, low pH, citrate and phorbol esters exhibits an outward rectification. Once activated the channel seems to be regulated in a calmodulin dependent manner, with a negative feedback mechanism.

Subunit : Homotetramer (Probable). Self-associates in a isoform-specific manner. Isoforms 1/A and 5/D but not isoform 2/B, 4/C and 6/E can oligomerize. Interacts with calmodulin. Interacts with Map7 and Src family Tyr protein kinases LYN, SRC, FYN, HCK, LCK and YES. Interacts with CTNNB1. The TRPV4 and CTNNB1 complex can interact with CDH1. Part of a complex containing MLC1, AQP4, HEPACAM and ATP1B1.

Subcellular Location : Cell membrane; Multi-pass membrane protein. Cell junction, adherens junction. Note=Assembly of the putative homotetramer occurs primarily in the endoplasmic reticulum. Isoform 1: Cell membrane. Isoform 5: Cell membrane.

Tissue Specificity : Found in the synoviocytes from patients with (RA) and without (CTR) rheumatoid arthritis (at protein level).

Similarity : Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV4 sub-subfamily.

Contains 3 ANK repeats.

全、新、優(yōu)、品、好四大特點：

瞬時受體電位蛋白12抗體規(guī)格 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標準品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細胞等，基本上各種科研所需產(chǎn)品在我司都能找到。

新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。

優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。

好：我公司具有優(yōu)質(zhì)的技術(shù)團隊，產(chǎn)品一旦售出，實驗過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。

正在熱銷的相關(guān)產(chǎn)品：

Anti-ULBP1/N2DL1/FITC 熒光素標記兔抗人、大、小鼠UL16結(jié)合蛋白1蛋白抗體IgGMulti-class antibodies規(guī)格： 0.2ml

VEGF(Vascular endothelial growth factor) 內(nèi)皮生長因子(多肽抗原)Multi-class antibodies規(guī)格： 0.5mg

CREB結(jié)合蛋白抗體 Anti-CBP 0.1ml

SYNPR/Synaptoporin 英文名稱： 突觸囊泡蛋白抗體 0.2ml

EDG1 英文名稱： 內(nèi)皮細胞分化鞘脂G蛋白偶聯(lián)受體1抗體 0.1ml

Rhesus antibody Rh Phospho-Histone H3 (Ser28) 磷酸化組蛋白H3抗體 規(guī)格 0.1ml

VEGF(Vascular endothelial growth factor) 內(nèi)皮生長因子(多肽抗原)Multi-class antibodies規(guī)格： 0.5mg

Gelsolin 凝溶膠蛋白抗原Multi-class antibodies規(guī)格： 0.5mg

FLT1 VEGFR1 / FLT-1 兔單抗 Human

Rhesus antibody Rh Phospho-Dab1 (Tyr220) 磷酸化Disabled 1抗體 規(guī)格 0.1ml

預(yù)染蛋白Marker分子量標準(10-260kDa) 2x250μl/50次 MBI原裝

ZNF268 英文名稱： 鋅指脂蛋白-1b抗體 0.2ml

DAB2IP 英文名稱： Dab2相互作用蛋白抗體 0.2ml

FLT1 VEGFR1 / FLT-1 兔單抗 Human

Cys-C(Mouse Cystatin C) ELISA Kit 小鼠半胱氨酸蛋白酶抑制劑/胱抑素CMulti-class antibodies規(guī)格： 48T

Anti-CD56/NCAM1/FITC 熒光素標記神經(jīng)細胞粘附分子1抗體IgGMulti-class antibodies規(guī)格： 0.2ml

Rhesus antibody Rh DPY19L4 DPY19L4蛋白抗體 規(guī)格 0.2ml

TOXO IgM 弓形蟲抗體 IgM(間接法二步法)

alpha MSH 英文名稱： 促黑細胞激素α抗體 0.1ml

APOB48R 英文名稱： 載脂蛋白B受體抗體 0.2ml

Anti-CD56/NCAM1/FITC 熒光素標記神經(jīng)細胞粘附分子1抗體IgGMulti-class antibodies規(guī)格： 0.2ml

人表皮生長因子受體(EGFR)ELISA試劑盒 96T/48T 試劑盒 組裝/原裝

豚鼠γ干擾素(IFN-γ)免疫試劑盒 guinea pig Ierferon γ ,IFN-γ ELISA Kit

四氫生物蝶呤(BH4)ELISA試劑盒 ，英文名： BH4 ELISA Kit

Mouseβmannosidase,βManaseELISA試劑盒小鼠β甘露糖苷酶(βManase)ELISA試劑盒規(guī)格：96T/48T

GoatTumornecrosisfactorα,TNF-αELISA試劑盒山羊壞死因子α(TNF-α)ELISA試劑盒規(guī)格：96T/48T

Humanai-cardiolipinaibodyIgA,ACA-IgAELISAKit人抗心磷脂抗體IgA(ACA-IgA)ELISA試劑盒規(guī)格：96T/48T

大鼠天門冬酸基轉(zhuǎn)移酶(AST)ELISA試劑盒 ，英文名： AST ELISA Kit

人凝溶膠蛋白(Gelsolin)ELISA檢測試劑盒HumanGelsolinELISAKit 96T/48T

駱駝ELISA試劑盒

CLIAKitforPsmAb(Humanai-presynapticmembraneaibody)ELISAKit人抗突觸前膜抗體規(guī)格：48T/96T

石蠟切片總膽固醇舒爾茨間接染色試劑盒10次

ELISAKitT人睪同規(guī)格：48T/96T

瞬時受體電位蛋白12抗體規(guī)格 大鼠纖溶酶原激活物抑制因子(PAI)ELISA試劑盒 ，英文名： PAI ELISA Kit

人型肝炎IgM(HCV-IgM)ELISA檢測試劑盒HumanHepatitisCvirusIgM,HCV-IgMELISAKit 96T/48T

大鼠5'-核苷酸酶,胞膜(5E/CD73)免疫試劑盒 Rat 5'-nucleotidase/cluster of differeiation 73,5E/CD73 ELISA kit

CLIAKitforsAC(HumanSolubleAdenylateCyclase)ELISAKit人可溶性腺苷酸環(huán)化酶規(guī)格：48T/96T

石蠟切片膠原纖維(SIRIUSRED)染色試劑盒50次

ELISAKitMyosin人肌球蛋白規(guī)格：48T/96T