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產(chǎn)地 | 進口、國產(chǎn) |
品牌 | 上海莼試 |
保存條件 | Store at -20 °C |
貨號 | CS11546 |
應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
CAS編號 | |
抗體名 | Anti-TBL1X |
克隆性 | |
靶點 | 詳見說明書 |
適應(yīng)物種 | 詳見說明書 |
形態(tài) | 詳見說明書 |
宿主 | 詳見說明書 |
亞型 | IgG |
標(biāo)識物 | 詳見說明書 |
濃度 | 1mg/1ml% |
免疫原 | KLH conjugated synthetic peptide derived from human TBL1X |
全、新、優(yōu)、品、好四大特點:
轉(zhuǎn)導(dǎo)素β1X連鎖蛋白抗體規(guī)格 全:公司提供上萬種產(chǎn)品,涵蓋了生物試劑,elisa試劑盒,標(biāo)準(zhǔn)品,培養(yǎng)基,原裝耗材,抗體、培養(yǎng)基、ATCC細胞等,基本上各種科研所需產(chǎn)品在我司都能找到。
新:產(chǎn)品更新速度較快,基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu):產(chǎn)品質(zhì)量好,投訴比較少。
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轉(zhuǎn)導(dǎo)素β1X連鎖蛋白抗體規(guī)格 英文名稱 Anti-TBL1X
中文名稱 轉(zhuǎn)導(dǎo)素β1X連鎖蛋白抗體規(guī)格
別 名 TBL1; EBI; F box like/WD repeat protein TBL1X; SMAP 55; SMAP55; TBL 1; TBL1X; Transducin (beta) like 1; Transducin (beta) like 1 X linked; Transducin beta like 1 X linked; Transducin beta like 1X; Transducin beta like 1X protein; TBL1X_HUMAN; F-box-like/WD repeat-containing protein TBL1X; Full=Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked. .
產(chǎn)品屬性:
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit
產(chǎn)品類型 一抗
研究領(lǐng)域 免疫學(xué) 染色質(zhì)和核信號 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo)
蛋白分子量 predicted molecular weight: 63kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human TBL1X
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
轉(zhuǎn)導(dǎo)素β1X連鎖蛋白抗體規(guī)格 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq].
Function : F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.
Subunit : Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2. Component of a E3 ubiquitin ligase complex containing UBE2D1, SIAH1, CACYBP/SIP, SKP1, APC and TBL1X. Probably part of other corepressor complexes, that do not contain NCOR1 and NCOR2. Interacts with histones H2B, H3a and H4.
Subcellular Location : Nucleus (Probable).
Tissue Specificity : Ubiquitous.
Similarity : Belongs to the WD repeat EBI family.
Contains 1 F-box-like domain.
Contains 1 LisH domain.
Contains 8 WD repeats.
Database links : UniProtKB/Swiss-Prot: O60907.3
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技術(shù)外包服務(wù):
★轉(zhuǎn)導(dǎo)素β1X連鎖蛋白抗體規(guī)格 分子生物學(xué):質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué):基因合成、引物合成、基因測序、載體構(gòu)建等
★蛋白工程:原核、哺乳動物蛋白表達系統(tǒng)等
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★抗體工程:磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
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