選擇性胸腺細胞相關(guān)蛋白抗體費用 英文名稱  Anti-THEMIS

中文名稱  選擇性胸腺細胞相關(guān)蛋白抗體費用 

別    名 C6orf190; C6orf207; MGC163388; Protein THEMIS; THEMIS; THMS1_HUMAN; Thymocyte expressed molecule involved in selection; Thymocyte selection associated; Thymocyte selection pathway associated; Thymocyte-expressed molecule involved in selection; TSEPA.

產(chǎn)品屬性：

濃    度  1mg/1ml

規(guī) 格  0.2ml/200μg

抗體來源  Rabbit

克隆類型   polyclonal

交叉反應   Human, Mouse, Rat, Dog, Pig, Horse, Rabbit

產(chǎn)品類型   一抗  

研究領(lǐng)域    干細胞 淋巴細胞 t-淋巴細胞

蛋白分子量  predicted molecular weight: 73kDa 

性    狀   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from Human THEMIS

亞    型  IgG

純化方法   affinity purified by Protein A

儲 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

選擇性胸腺細胞相關(guān)蛋白抗體費用 產(chǎn)品應用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蠟切片需做抗原修復） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 Themis is a 641 amino acid nuclear and cytoplasmic protein that exists as three alternatively spliced isoforms. Themis belongs to the themis family and interacts with PLC γ1, Emt and GRB2. Acting through T-cell antigen receptor (TCR) signaling and through the regulation of calcium influx and phosphorylation of ERK 1, Themis plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Themis is phosphorylated on Tyr residues quickly after TCR stimulation. The gene that encodes Themis maps to human chromosome 6q22.33. With 170 million base pairs, chromosome 6 comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Function : Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.

Subcellular Location : Cytoplasm. Nucleus.

Post-translational modifications : Phosphorylated on Tyr residues quickly after TCR stimulation.

Similarity : Belongs to the themis family.

Database links : UniProtKB/Swiss-Prot: Q8N1K5.3

實驗流程：

全、新、優(yōu)、品、好四大特點：

選擇性胸腺細胞相關(guān)蛋白抗體費用 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標準品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細胞等，基本上各種科研所需產(chǎn)品在我司都能找到。

新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。

優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。

好：我公司具有優(yōu)質(zhì)的技術(shù)團隊，產(chǎn)品一旦售出，實驗過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。

正在熱銷的相關(guān)產(chǎn)品：

Anti-VCAM-1/FITC(CD106) 熒光素標記內(nèi)皮細胞粘附分子抗體IgGMulti-class antibodies規(guī)格： 0.2ml

CD33/Siglec-3(mouse ret) CD33抗原(大、小鼠)Multi-class antibodies規(guī)格： 0.5mg

細胞表面趨化因子受體7抗體 Anti-CCR-7 0.1ml

STK36 英文名稱： 絲酸/蘇酸激酶36融合同源蛋白抗體 0.2ml

ENC1 英文名稱： 外胚層神經(jīng)皮層蛋白1抗體 0.2ml

Rhesus antibody Rh Phospho-HER2(Tyr1248) 磷酸化HER2受體抗體 規(guī)格 0.1ml

CD33/Siglec-3(mouse ret) CD33抗原(大、小鼠)Multi-class antibodies規(guī)格： 0.5mg

Anti-TGF- BetaR 2/FITC 熒光素標記轉(zhuǎn)移生長因子–β受體2抗體IgGMulti-class antibodies規(guī)格： 0.2ml

NKB (Neurokinins B) 神經(jīng)激肽B(抗原)Multi-class antibodies規(guī)格： 0.5mg

抗相關(guān)抗原5抗體 Anti-SPAG5/map126 0.1ml

SERPINB12 英文名稱： 絲酸蛋白酶抑制劑B12抗體 0.2ml

EHM2 英文名稱： EHM2蛋白抗體 0.2ml

Rhesus antibody Rh phospho-MAP4K4(Ser801) 磷酸化原活化蛋白激酶MAP4K4抗體 規(guī)格 0.1ml

NKB (Neurokinins B) 神經(jīng)激肽B(抗原)Multi-class antibodies規(guī)格： 0.5mg

PAK7/PAK5/MBT 激活激酶PAK7/PAK5抗原Multi-class antibodies規(guī)格： 0.5mg

Anti-ATF2 活化復制因子2抗體Multi-class antibodies規(guī)格： 0.1ml

Rhesus antibody Rh phospho-APP/ABPP (Ser730) 磷酸化APP淀粉樣肽前體蛋白抗體 規(guī)格 0.1ml

Somatostatin 生長抑素 濃縮液 0.1ml 進口分裝

UBE2D4 英文名稱： 泛素蛋白連接酶D4抗體 0.2ml

DDRGK1 英文名稱： DDRGK1蛋白抗體 0.2ml

Anti-ATF2 活化復制因子2抗體Multi-class antibodies規(guī)格： 0.1ml

IL2 Protein Canine 重組狗 Ierleukin-2 / IL-2 蛋白 (147 Cys/Ser)

III型膠原酶(含100mL酶解緩沖液) 10mL

NRG1 Others Human 人 NRG1-beta 1 (EGF Domain) 人細胞裂解液 (陽性對照)

NCI-N87 [N87]人細胞 NCI-N87 human gasic cancer cells [N87] RPMI-1640(GIBCO)+10%FBS

非洲綠猴腎細胞系/HCV-E1;Vero-HCV-E1

人外殼細胞(HHorSC)( 5×105 ) CSC, 小鼠心肌細胞 Mouse

CM-H073人膀胱成纖維細胞完全培養(yǎng)基100mL

TNFRSF10D Others Cynomolgus 食蟹猴 AIL R4 / CD264 / TNFRSF10D 人細胞裂解液 (陽性對照)

人真皮成纖維母細胞-新生HDF-n

RWPE-1細胞，人正常上皮細胞 小鼠B淋巴細胞雜交瘤細胞,SH3細胞 成纖維細胞培養(yǎng)基-2(用于心肌成纖維細胞)FM-2

MDA-MB-157(人癌細胞) 5×106cells/瓶×2

Anglne(人細胞) 5×106cells/瓶×2 CM-R067大鼠腎足突細胞完全培養(yǎng)基100mL 人胚腎細胞-F克隆;293F

選擇性胸腺細胞相關(guān)蛋白抗體費用 IL2 Protein Canine 重組狗 Ierleukin-2 / IL-2 蛋白 (147 Cys/Ser)

III型膠原酶(含100mL酶解緩沖液) 10mL

NRG1 Others Human 人 NRG1-beta 1 (EGF Domain) 人細胞裂解液 (陽性對照)

NCI-N87 [N87]人細胞 NCI-N87 human gasic cancer cells [N87] RPMI-1640(GIBCO)+10%FBS

非洲綠猴腎細胞系/HCV-E1;Vero-HCV-E1

人外殼細胞(HHorSC)( 5×105 ) CSC, 小鼠心肌細胞 Mouse

技術(shù)外包服務:

★選擇性胸腺細胞相關(guān)蛋白抗體費用 分子生物學：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學：基因合成、引物合成、基因測序、載體構(gòu)建等

★蛋白工程：原核、哺乳動物蛋白表達系統(tǒng)等

★病毒包裝：腺病毒、慢病毒等

★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★細胞工程：細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構(gòu)建、細胞RNAi技術(shù)等等。