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產(chǎn)地 | 進口、國產(chǎn) |
品牌 | 上海莼試 |
保存條件 | Store at -20 °C |
貨號 | CS11396 |
應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
CAS編號 | |
抗體名 | Anti-STOM/Stomatin |
克隆性 | |
靶點 | 詳見說明書 |
適應(yīng)物種 | 詳見說明書 |
形態(tài) | 詳見說明書 |
宿主 | 詳見說明書 |
亞型 | IgG |
標(biāo)識物 | 詳見說明書 |
濃度 | 1mg/1ml% |
免疫原 | KLH conjugated synthetic peptide derived from human STOM/Stomatin (166-203aa) |
技術(shù)外包服務(wù):
★紅細胞膜蛋白STOM抗體說明書 分子生物學(xué):質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué):基因合成、引物合成、基因測序、載體構(gòu)建等
★蛋白工程:原核、哺乳動物蛋白表達系統(tǒng)等
★病毒包裝:腺病毒、慢病毒等
★抗體工程:磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細胞工程:細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構(gòu)建、細胞RNAi技術(shù)等等。
實驗流程:
紅細胞膜蛋白STOM抗體說明書 英文名稱 Anti-STOM/Stomatin
中文名稱 紅細胞膜蛋白STOM抗體說明書
別 名 BND7; EPB7; EPB72; Erythrocyte band 7 integral membrane protein; Erythrocyte membrane protein band 7.2 (stomatin); Protein 7.2b; STOM; STOM_HUMAN; Stomatin.
產(chǎn)品屬性:
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep
產(chǎn)品類型 一抗
研究領(lǐng)域 細胞生物 神經(jīng)生物學(xué) 通道蛋白 細胞膜受體
蛋白分子量 predicted molecular weight: 32kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human STOM/Stomatin (166-203aa)
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
紅細胞膜蛋白STOM抗體說明書 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Stomatin is an integral membrane protein found in lipid/protein-rich microdomains of almost all human tissues. It was named after the rare human disease haemolytic anaemia hereditary stomatocytosis. Stomatin is implicated in signal transduction and cell communication, and it may regulate cation movement through ion channels and transporters. Absence of Stomatin may cause Na+ and K+ ions to leak into and from erythrocytes. A second function of Stomatin may be to act as a cytoskeletal anchor. Stomatin is a major lipid-raft component of erythrocytes and epithelial cells, and is also an abundant platelet protein. It contains a single hydrophobic domain, close to the N-terminus, and a phosphorylation site.
Function : Thought to regulate cation conductance. May regulate ACCN1 and ACCN3 gating.
Subunit : Homooligomer containing between 9 and 12 monomers. Interacts with ASIC1, ASIC2 and ASIC3 (By similarity). Interacts with LANCL1.
Subcellular Location : Cell membrane. Cell membrane. Melanosome. Exposed on the cytoplasmic surface of the membrane. Associated with lipid rafts. Concentrates preferentially in plasma membrane protrusions and in a juxta-nuclear region which may represent Golgi-derived vesicles. Colocalizes with actin. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity : Widely expressed.
Similarity : Belongs to the band 7/mec-2 family.
Database links : UniProtKB/Swiss-Prot: P27105.3
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新:產(chǎn)品更新速度較快,基本上每周都有新產(chǎn)品出現(xiàn)。
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