全、新、優(yōu)、品、好四大特點：

精氨酸結(jié)合蛋白2抗體說明書 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標準品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細胞等，基本上各種科研所需產(chǎn)品在我司都能找到。

新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。

優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。

好：我公司具有優(yōu)質(zhì)的技術(shù)團隊，產(chǎn)品一旦售出，實驗過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。

精氨酸結(jié)合蛋白2抗體說明書 英文名稱  Anti-SORBS2/ArgBP2

中文名稱  精氨酸結(jié)合蛋白2抗體說明書 

別    名 Arg binding protein 2; Arg/Abl interacting protein 2; Arg/Abl interacting protein; ARGBP2; PRO0618; SRBS2_HUMAN; sorbin and SH3 domain containing 2.

產(chǎn)品屬性：

濃    度  1mg/1ml

規(guī) 格  0.2ml/200μg

抗體來源  Rabbit

克隆類型   polyclonal

交叉反應   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, G

產(chǎn)品類型   一抗  

研究領(lǐng)域    信號轉(zhuǎn)導 激酶和磷酸酶

蛋白分子量  predicted molecular weight: 124kDa 

性    狀   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from hu SORBS2/ArgBP2

亞    型  IgG

純化方法   affinity purified by Protein A

儲 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

精氨酸結(jié)合蛋白2抗體說明書 產(chǎn)品應用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

（石蠟切片需做抗原修復） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 SORBS2 is an adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. It can form a complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1.

Function : Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

Subunit : Interacts with ABL, CBL, DNM1, DNM2, FLOT1, MLLT4/afadin, PTK2B/PYK2, SAPAP, SPTAN1, SYNJ1, SYNJ2, VCL/vinculin, and WASF (By similarity). Interacts with ABL1/c-Abl, ABL2/v-Abl/Arg, ACTN, AKT1, CBL, PALLD and PAK1.

Subcellular Location : Cytoplasm, perinuclear region. Note=Found at the Z-disk sarcomeres, stress fibers, dense bodies and focal adhesion.

Tissue Specificity : Abundantly expressed in heart. In cardiac muscle cells, located in the Z-disks of sarcomere. Also found, but to a lower extent, in small and large intestine, pancreas, thymus, colon, spleen, prostate, testis, brain, ovary and epithelial cells.

Post-translational modifications : Ubiquitinated by CBL.

Similarity : Contains 3 SH3 domains.

Contains 1 SoHo domain.

Database links : UniProtKB/Swiss-Prot: O94875.3

實驗流程：

正在熱銷的相關(guān)產(chǎn)品：

Anti-Tie1/FITC 熒光素標記生成素-1受體抗體IgGMulti-class antibodies規(guī)格： 0.2ml

ATM(ataxia telangiectasia mutated) 性癥突變蛋白抗原Multi-class antibodies規(guī)格： 0.5mg

抗spindly抗體 anti-SPY 0.1ml

SCN11A 英文名稱： 通道蛋白11α抗體 0.2ml

EGFP 英文名稱： 重組增強型綠色熒光蛋白抗體 0.1ml

Rhesus antibody Rh phospho-MAP4(Ser1073) 磷酸化微管相關(guān)蛋白4抗體 規(guī)格 0.1ml

ATM(ataxia telangiectasia mutated) 性癥突變蛋白抗原Multi-class antibodies規(guī)格： 0.5mg

Anti-TRAF3/CD40bp /FITC 熒光素標記CD40結(jié)合蛋白/CD40受體相關(guān)因子1抗體IgGMulti-class antibodies規(guī)格： 0.2ml

PTP-1B (Protein-tyrosine phosphatase, non-receptor ) 蛋白酪氨酸磷酸酶-1B(抗原)Multi-class antibodies規(guī)格： 0.5mg

轉(zhuǎn)甲狀腺素蛋白抗體 Anti-Transthyretin 0.2ml

14-3-3 family protein 英文名稱： 蘋果14-3-3蛋白抗體(植物) 1ml

EIF5 英文名稱： 真核翻譯起始因子5抗體 0.2ml

Rhesus antibody Rh phospho-IRS1(Thr176) 磷酸化受體底物1抗體 規(guī)格 0.1ml

PTP-1B (Protein-tyrosine phosphatase, non-receptor ) 蛋白酪氨酸磷酸酶-1B(抗原)Multi-class antibodies規(guī)格： 0.5mg

S100B S100B蛋白抗原Multi-class antibodies規(guī)格： 0.5ml

Anti-Bcl-10/CLAP Bcl-10抗體Multi-class antibodies規(guī)格： 0.2ml

Rhesus antibody Rh PHGDH 磷酸甘油酸脫氫酶抗體 規(guī)格 0.2ml

IGF-1R 濃縮液 0.1ml 進口分裝

URG4 英文名稱： 上調(diào)基因4抗體(N端) 0.2ml

C16orf72 英文名稱： 16號染色體開放閱讀框72抗體 0.1ml

Anti-Bcl-10/CLAP Bcl-10抗體Multi-class antibodies規(guī)格： 0.2ml

OSM Protein Mouse 重組小鼠 Oncostatin M / OSM 蛋白 (His 標簽)

小鼠肝內(nèi)膽管上皮細胞完全培養(yǎng)基 100mL

IgG3 Others Mouse 小鼠 IgG3-Fc 人細胞裂解液 (陽性對照)

MC3T3-E1 Subclone 14小鼠顱頂前骨細胞亞克隆14 MC3T3-E1 Subclone 14 in mouse parietal bone cell sub clone 14 before a-MEM培養(yǎng)基+10%FBS

CL-0119HuH-6(人肝母細胞瘤細胞)5×106cells/瓶×2

RS1(大鼠皮膚成纖維樣細胞) 5×106cells/瓶×2 THP-1(人單核細胞)

CM-M091小鼠成骨細胞完全培養(yǎng)基100mL

TNFSF12 Others Cynomolgus 食蟹猴 / 人 TNFSF12 人細胞裂解液 (陽性對照)

成骨細胞培養(yǎng)基ObM-prf

HeLa229細胞，人細胞(HPV-18永生化細胞) 小鼠細胞,GT1-1細胞 真皮成纖維細胞Many types of cells包裝：5 × 105次方(1ml)

HBE(人上皮樣細胞) 5×106cells/瓶×2

hMSC-AT Pellet 人體脂肪組織的間質(zhì)干細胞團塊 > 1 mio.cells 人腎皮質(zhì)上皮細胞總RNAHRCEpiC NA

精氨酸結(jié)合蛋白2抗體說明書 OSM Protein Mouse 重組小鼠 Oncostatin M / OSM 蛋白 (His 標簽)

小鼠肝內(nèi)膽管上皮細胞完全培養(yǎng)基 100mL

IgG3 Others Mouse 小鼠 IgG3-Fc 人細胞裂解液 (陽性對照)

MC3T3-E1 Subclone 14小鼠顱頂前骨細胞亞克隆14 MC3T3-E1 Subclone 14 in mouse parietal bone cell sub clone 14 before a-MEM培養(yǎng)基+10%FBS

CL-0119HuH-6(人肝母細胞瘤細胞)5×106cells/瓶×2

RS1(大鼠皮膚成纖維樣細胞) 5×106cells/瓶×2 THP-1(人單核細胞)

技術(shù)外包服務:

★精氨酸結(jié)合蛋白2抗體說明書 分子生物學：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學：基因合成、引物合成、基因測序、載體構(gòu)建等

★蛋白工程：原核、哺乳動物蛋白表達系統(tǒng)等

★病毒包裝：腺病毒、慢病毒等

★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★細胞工程：細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構(gòu)建、細胞RNAi技術(shù)等等。