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超氧化物歧化酶4抗體費(fèi)用
  • 品牌:上海莼試
  • 產(chǎn)地:進(jìn)口、國(guó)產(chǎn)
  • 貨號(hào):CS11313
  • 發(fā)布日期: 2019-01-14
  • 更新日期: 2025-03-20
產(chǎn)品詳請(qǐng)
產(chǎn)地 進(jìn)口、國(guó)產(chǎn)
品牌 上海莼試
保存條件 Store at -20 °C
貨號(hào) CS11313
應(yīng)用范圍 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
CAS編號(hào)
抗體名 Anti-SOD4/CCS
克隆性
靶點(diǎn) 詳見說(shuō)明書
適應(yīng)物種 詳見說(shuō)明書
形態(tài) 詳見說(shuō)明書
宿主 詳見說(shuō)明書
亞型 IgG
標(biāo)識(shí)物 詳見說(shuō)明書
濃度 1mg/1ml%
免疫原 KLH conjugated synthetic peptide derived from human SOD4 (211-250aa)

全、新、優(yōu)、品、好四大特點(diǎn):

超氧化物歧化酶4抗體費(fèi)用 全:公司提供上萬(wàn)種產(chǎn)品,涵蓋了生物試劑,elisa試劑盒,標(biāo)準(zhǔn)品,培養(yǎng)基,原裝耗材,抗體、培養(yǎng)基、ATCC細(xì)胞等,基本上各種科研所需產(chǎn)品在我司都能找到。

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超氧化物歧化酶4抗體費(fèi)用 英文名稱  Anti-SOD4/CCS

中文名稱  超氧化物歧化酶4抗體費(fèi)用 

     CCS; CCS_HUMAN; Copper chaperone for superoxide dismutase; MGC138260; SOD 4; SOD4; Superoxide dismutase copper chaperone.

產(chǎn)品屬性:

      1mg/1ml

規(guī)   0.2ml/200μg

抗體來(lái)源  Rabbit

克隆類型   polyclonal

交叉反應(yīng)   Human, Mouse, Rat, Dog, Pig, Horse, Rabbit

產(chǎn)品類型   一抗  

研究領(lǐng)域     細(xì)胞生物 免疫學(xué) 線粒體

蛋白分子量  predicted molecular weight: 29kDa 

       Lyophilized or Liquid

  KLH conjugated synthetic peptide derived from human SOD4 (211-250aa)

      IgG

純化方法   affinity purified by Protein A

儲(chǔ)    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

超氧化物歧化酶4抗體費(fèi)用 產(chǎn)品應(yīng)用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

(石蠟切片需做抗原修復(fù)) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.

Function : Delivers copper to copper zinc superoxide dismutase (SOD1).

Subunit : Homodimer, and heterodimer with SOD1. Interacts with COMMD1. Interacts with XIAP/BIRC4.

Subcellular Location : Cytoplasm.

Tissue Specificity : Ubiquitous.

Post-translational modifications : Ubiquitinion by XIAP/BIRC4 leads to enhancement of its chaperone activity toward its physiologic target, SOD1, rather than proteasomal degradation. XIAP/BIRC4 preferentially ubiquitinates at Lys-241.

Similarity : In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.Contains 1 HMA domain.

Database links : UniProtKB/Swiss-Prot: O14618.1

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