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肌萎縮相關蛋白1抗體費用 英文名稱  Anti-RERE

中文名稱  肌萎縮相關蛋白1抗體費用 

別    名 ARG; arginine glutamic acid dipeptide (RE) repeats; arginine glutamic acid dipeptide repeats; Arginine glutamic acid dipeptide repeats protein; Arginine-glutamic acid dipeptide repeats protein; ARGININE-GLUTAMIC ACID REPEATS-ENCODING GENE; ARP; ATN1L; Atr2; atrophin 1 like; Atrophin 1 like protein; Atrophin 1 related protein; atrophin 2; atrophin related protein; ATROPHIN-1-ASSOCIATED PROTEIN; Atrophin-1-like protein; Atrophin-1-related protein; atrophin-2; ATROPHIN-RELATED PROTEIN; DNB1; Rere; RERE_HUMAN.

產品屬性：

濃    度  1mg/1ml

規(guī) 格  0.2ml/200μg

抗體來源  Rabbit

克隆類型   polyclonal

交叉反應   Human, Mouse, Rat, Chicken, Dog, Cow, Horse

產品類型   一抗  

研究領域    細胞生物 信號轉導 細胞凋亡 轉錄調節(jié)因子 表觀遺傳學

蛋白分子量  predicted molecular weight: 172kDa 

性    狀   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human RERE

亞    型  IgG

純化方法   affinity purified by Protein A

儲 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

肌萎縮相關蛋白1抗體費用 產品應用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蠟切片需做抗原修復） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產品介紹 FunctionPlays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.

Function : Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.

Subunit : Interacts with HDAC1 (By similarity). Interacts with ATN1. Interaction with ATN1 is improved when the poly-Gln region of ATN1 is extended. Interacts with FAT1.

Subcellular Location : Nucleus. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.

Tissue Specificity : Widely expressed. Expressed in tumor cell lines.

DISEASE : Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line NGP. Translocation t(1;15)(p36.2;q24).

Similarity : Contains 1 BAH domain.

Contains 1 ELM2 domain.

Contains 1 GATA-type zinc finger.

Contains 1 SANT domain.

Database links : UniProtKB/Swiss-Prot: Q9P2R6.2

實驗流程：

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