全、新、優(yōu)、品、好四大特點(diǎn)：

環(huán)指蛋白111抗體品牌 全：公司提供上萬(wàn)種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標(biāo)準(zhǔn)品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細(xì)胞等，基本上各種科研所需產(chǎn)品在我司都能找到。

新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。

優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。

好：我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊(duì)，產(chǎn)品一旦售出，實(shí)驗(yàn)過(guò)程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時(shí)沒(méi)有任何的后顧之憂。

環(huán)指蛋白111抗體品牌 英文名稱  Anti-RNF111

中文名稱  環(huán)指蛋白111抗體品牌 

別    名 ARK; Arkadia; DKFZp313E0731; DKFZp686H1966; DKFZp761D081; E3 ubiquitin protein ligase Arkadia; FLJ38008; Ring finger protein 111; RNF 111; RN111_HUMAN.

產(chǎn)品屬性：

濃    度  1mg/1ml

規(guī) 格  0.2ml/200μg

抗體來(lái)源  Rabbit

克隆類型   polyclonal

交叉反應(yīng)   Human, Mouse, Rat, Dog, Pig, Rabbit, Sheep

產(chǎn)品類型   一抗  

研究領(lǐng)域    細(xì)胞生物 免疫學(xué)

蛋白分子量  predicted molecular weight: 109kDa 

性    狀   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human RNF111

亞    型  IgG

純化方法   affinity purified by Protein A

儲(chǔ) 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

環(huán)指蛋白111抗體品牌 產(chǎn)品應(yīng)用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

（石蠟切片需做抗原修復(fù)） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 RNF111 (Ring finger protein 111) acts in the NODAL pathway of mesoderm patterning during embryonic development. It is an E3 ubiquitin-protein ligase which promotes the ubiquitination of inhibitory SMADs such as SMAD7, induces their proteasomal degradation and thereby enhances the transcriptional activity of TGF-beta and BMP. It also induces degradation of the transriptional repressors SnoN and c-Ski. RNF111, therefore, effectively enhances TGF-beta signaling through simultaneous down-regulation of two distinct types of negative regulators, Smad7 and SnoN/c-Ski.

Function : Acts in the NODAL pathway of mesoderm patterning during embryonic development. Acts downstream AXIN1 as an E3 ubiquitin-protein ligase which promotes the ubiquitination of inhibitory SMADs such as SMAD7, induces their proteasomal degradation and thereby enhances the transcriptional activity of TGF-beta and BMP. Activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation.

Subunit : Interacts with SMAD6, SMAD7, AXIN1, AXIN2 and SKIL isoform SNON. Part of a complex containing RNF111, AXIN1 and SMAD7. Interacts (via SIM domains) with SUMO1 and SUMO2.

Subcellular Location : Cytoplasmic and Nuclear

Tissue Specificity : Broadly expressed.

Similarity : Contains 1 RING-type zinc finger.

Database links : UniProtKB/Swiss-Prot: Q6ZNA4.3

實(shí)驗(yàn)流程：

正在熱銷的相關(guān)產(chǎn)品：

Anti-TRH/FITC 熒光素標(biāo)記促甲狀腺素釋放激素抗體IgGMulti-class antibodies規(guī)格： 0.2ml

CA15-3 peptide 癌相關(guān)抗原抗原Multi-class antibodies規(guī)格： 0.5mg

阻抑基因1抗體 Anti-TSLC1 0.2ml

STIP1 英文名稱： 應(yīng)激誘導(dǎo)磷蛋白1抗體 0.2ml

Endomucin 英文名稱： 內(nèi)皮粘蛋白EMCN抗體 0.2ml

Rhesus antibody Rh Phospho-IRAK1 (Thr387) 磷酸化白介素-1受體相關(guān)激酶1抗體 規(guī)格 0.1ml

CA15-3 peptide 癌相關(guān)抗原抗原Multi-class antibodies規(guī)格： 0.5mg

Anti-Phospho-p63 (Ser455)/FITC 熒光素標(biāo)記磷酸化P63抑制基因抗體IgGMulti-class antibodies規(guī)格： 0.2ml

Rabbit Anti-monkey IgM/Biotin 生物素化兔抗猴IgMMulti-class antibodies規(guī)格： 0.3ml

間隙連接蛋白45抗體 Anti-CX45 0.1ml

Goat Anti-Mouse IgM/PE-Cy5.5 PE-Cy5.5標(biāo)記的羊抗小鼠IgM 0.1ml

FOXF1 英文名稱： 叉頭蛋白F1抗體 0.2ml

Rhesus antibody Rh Phospho-Vimentin(Ser82) 磷酸化波形蛋白抗體 規(guī)格 0.1ml

Rabbit Anti-monkey IgM/Biotin 生物素化兔抗猴IgMMulti-class antibodies規(guī)格： 0.3ml

EPO 小鼠促紅細(xì)胞生成素Multi-class antibodies規(guī)格： 48T

Anti-FGFR3/CD333 成纖維細(xì)胞生長(zhǎng)因子受體3抗體Multi-class antibodies規(guī)格： 0.2ml

Rhesus antibody Rh Mouse Anti-Rabbit IgM/Cy3 Cy3標(biāo)記的小鼠抗兔IgM 規(guī)格 0.1ml

ATF-1(Human activating transcription factor-1) ELISA Kit 人轉(zhuǎn)錄因子抗體-1 96T

STK33 英文名稱： 絲酸/蘇酸激酶33抗體 0.2ml

CDC37L1 英文名稱： 細(xì)胞分裂周期37樣蛋白1抗體 0.2ml

Anti-FGFR3/CD333 成纖維細(xì)胞生長(zhǎng)因子受體3抗體Multi-class antibodies規(guī)格： 0.2ml

PAC斜面培養(yǎng)基250g用于弧菌的保存

Ironbacteriamedium

葡萄糖酪胨瓊脂 Dextrose Casein-peptone Agar 250 用于食品中臘樣芽胞桿菌鑒定和計(jì)數(shù)(APHA方法)

山梨醇麥康凱半固體培養(yǎng)基250g/瓶用于O種保存incubationmedia山梨醇麥康凱半固體培養(yǎng)基250g/瓶用于O種保存

孟加拉紅培養(yǎng)基平板(9cm) 10個(gè)/包 用于食品中霉菌及酵母菌總數(shù)測(cè)定

Mannitol-Egg-Yolk-PolymycinAgarBase,Modified

桔汁瓊脂 ORANGE SERUM AGAR 用于飲料中耐酸細(xì)菌的分離培養(yǎng)

堿性瓊脂平板 Alkaline Agar 250 用于分離霍亂弧菌

80-玉米瓊脂培養(yǎng)基250g/瓶用于白色念珠菌產(chǎn)芽管試驗(yàn)，每500ml培養(yǎng)基中添加0204incubationmedia80-玉米瓊脂培養(yǎng)基250g/瓶用于白色念珠菌產(chǎn)芽管試驗(yàn)，每500ml培養(yǎng)基中添加0204

PBS-Tween20洗液 250g 大腸桿菌O157免疫磁珠試

環(huán)指蛋白111抗體品牌 亞碲酸(山梨醇麥康凱培養(yǎng)基凍干配套試劑)  規(guī)格：  10支/盒  用途：  每支添加于500ml（025102）中配成山梨醇麥康凱培養(yǎng)基

頭孢磺啶(MUGal肉湯凍干配套試劑)  規(guī)格：  10支/盒  用途：  每支添加于100ml（022051）中配成MUGal肉湯

茚三試劑（馬尿酸鹽試劑）  規(guī)格：  10ml/支  用途：  用于馬尿酸鹽實(shí)驗(yàn)

氏試劑  規(guī)格：  10ml/支  用途：  用于綠膿桿菌分解乙酰胺產(chǎn)試驗(yàn)

技術(shù)外包服務(wù):

★環(huán)指蛋白111抗體品牌 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測(cè)序、載體構(gòu)建等

★蛋白工程：原核、哺乳動(dòng)物蛋白表達(dá)系統(tǒng)等

★病毒包裝：腺病毒、慢病毒等

★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★細(xì)胞工程：細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。