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Rho家族GTP酶3抗體說(shuō)明書
  • 品牌:上海莼試
  • 產(chǎn)地:進(jìn)口、國(guó)產(chǎn)
  • 貨號(hào):CS10892
  • 發(fā)布日期: 2019-01-04
  • 更新日期: 2025-04-18
產(chǎn)品詳請(qǐng)
產(chǎn)地 進(jìn)口、國(guó)產(chǎn)
品牌 上海莼試
保存條件 Store at -20 °C
貨號(hào) CS10892
應(yīng)用范圍 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
CAS編號(hào)
抗體名 Anti-RND3/RHOE
克隆性
靶點(diǎn) 詳見(jiàn)說(shuō)明書
適應(yīng)物種 詳見(jiàn)說(shuō)明書
形態(tài) 詳見(jiàn)說(shuō)明書
宿主 詳見(jiàn)說(shuō)明書
亞型 IgG
標(biāo)識(shí)物 詳見(jiàn)說(shuō)明書
濃度 1mg/1ml%
免疫原 KLH conjugated synthetic peptide derived from human RND3

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Rho家族GTP酶3抗體說(shuō)明書 英文名稱  Anti-RND3/RHOE

中文名稱  Rho家族GTP酶3抗體說(shuō)明書 

     ARHE; memB; Rho family GTPase 3; Rho8; RhoE; RND3_HUMAN.

產(chǎn)品屬性:

      1mg/1ml

規(guī)   0.1ml/100μg 0.2ml/200μg

抗體來(lái)源  Rabbit

克隆類型   polyclonal

交叉反應(yīng)   Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit

產(chǎn)品類型   一抗  

研究領(lǐng)域     細(xì)胞生物 染色質(zhì)和核信號(hào) 信號(hào)轉(zhuǎn)導(dǎo)

蛋白分子量  predicted molecular weight: 27kDa 

       Lyophilized or Liquid

  KLH conjugated synthetic peptide derived from human RND3

      IgG

純化方法   affinity purified by Protein A

儲(chǔ)    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Rho家族GTP酶3抗體說(shuō)明書 產(chǎn)品應(yīng)用   ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

(石蠟切片需做抗原修復(fù)) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 The Rho family of proteins mediates cytoskeleton organization and cell motility responses. This family contains twenty different members divided into five groups, the Rho-like, Rac-like, Cdc42-like, Rnd and RhoBTB subfamilies. Rho proteins have GTPase activity and bind GTP in their active form and GDP in their inactive form. In their active form they interact with downstream proteins. However, the Rnd subfamily of proteins containing the Rnd1, Rnd2 and RhoE(Rnd3), binds GTP but not GDP and has no GTPase activity. While Rho proteins are required for stress fibre formation in cultured fibroblasts, epithelial and endothelial cells, overexpression of Rnd3 or Rnd1 in the same cells may cause an opposite effect (i.e. decrease in stress fibre). Thus, the Rnd3 protein may act as an antagonist for the Rho proteins either by directly binding to Rho or to other downstream proteins.

Subunit : Binds ROCK1 (By similarity). Interacts with UBXD5.

Subcellular Location : Golgi Apparatus; Golgi apparatus membrane; peripheral membrane protein.

Tissue Specificity : Ubiquitous.

Similarity : Belongs to the small GTPase superfamily. Rho family.

實(shí)驗(yàn)流程:

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