全、新、優(yōu)、品、好四大特點(diǎn)：

蛋白酶體PSMD3抗體規(guī)格 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標(biāo)準(zhǔn)品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細(xì)胞等，基本上各種科研所需產(chǎn)品在我司都能找到。

新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。

優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。

好：我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊(duì)，產(chǎn)品一旦售出，實(shí)驗(yàn)過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。

蛋白酶體PSMD3抗體規(guī)格 英文名稱  Anti-Proteasome 19S S3

中文名稱  蛋白酶體PSMD3抗體規(guī)格 

別    名 26S proteasome non ATPase regulatory subunit 3; 26S proteasome non-ATPase regulatory subunit 3; 26S proteasome regulatory subunit RPN3; 26S proteasome regulatory subunit S3; P58; Proteasome (prosome, macropain) 26S subunit non ATPase 3; Proteasome subunit p58; PSMD3; PSMD3_HUMAN; RPN3; S3 antibody Tissue specific transplantation antigen 2; TSTA2.

產(chǎn)品屬性：

濃    度  1mg/1ml

規(guī) 格  0.2ml/200μg

抗體來源  Rabbit

克隆類型   polyclonal

交叉反應(yīng)   Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep

產(chǎn)品類型   一抗  

研究領(lǐng)域    細(xì)胞生物 免疫學(xué)

蛋白分子量  predicted molecular weight: 61kDa 

性    狀   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human Proteasome 19S 10B

亞    型  IgG

純化方法   affinity purified by Protein A

儲 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

蛋白酶體PSMD3抗體規(guī)格 產(chǎn)品應(yīng)用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

（石蠟切片需做抗原修復(fù)） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.

Function : Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.

Subunit : The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively.

Subcellular Location : Cytoplasm.

Contains 1 PCI domain.

Database links : UniProtKB/Swiss-Prot: O43242.2

(proteasomes)蛋白酶體的主要作用是降解細(xì)胞不需要的或受到損傷的蛋白質(zhì)，這一作用是通過打斷肽鍵的化學(xué)反應(yīng)來實(shí)現(xiàn)。能夠發(fā)揮這一作用的酶被稱為蛋白酶。蛋白酶體是細(xì)胞用來調(diào)控特定蛋白質(zhì)和除去錯誤折疊蛋白質(zhì)的主要機(jī)制。經(jīng)過蛋白酶體的降解，蛋白質(zhì)被切割為約7-8個氨基酸長的肽段；這些肽段可以被進(jìn)一步降解為單個氨基酸分子，然后被用于合成新的蛋白質(zhì)。需要被降解的蛋白質(zhì)會先被一個稱為泛素的小型蛋白質(zhì)所標(biāo)記（即連接上）。這一標(biāo)記反應(yīng)是被泛素連接酶所催化。一旦一個蛋白質(zhì)被標(biāo)記上一個泛素分子，就會引發(fā)其它連接酶加上更多的泛素分子；這就形成了可以與蛋白酶體結(jié)合的“多泛素鏈”，從而將蛋白酶體帶到這一標(biāo)記的蛋白質(zhì)上，開始其降解過程。蛋白酶體降解途徑對于許多細(xì)胞進(jìn)程，包括細(xì)胞周期、基因表達(dá)的調(diào)控、氧化應(yīng)激反應(yīng)等，都是必不可少的。

實(shí)驗(yàn)流程：

正在熱銷的相關(guān)產(chǎn)品：

Anti-C-Met/HGFR/HRP 辣根過氧化物酶標(biāo)記肝細(xì)胞生長因子受體(原癌基因蛋白)抗體IgGMulti-class antibodies規(guī)格： 0.2ml

Anti-JAK1/FITC 熒光素標(biāo)記蛋白質(zhì)酪氨酸激酶JAK-1抗體IgGMulti-class antibodies規(guī)格： 0.2ml

Rhesus antibody Rh CCDC7 卷曲螺旋結(jié)構(gòu)域蛋白7抗體 規(guī)格 0.2ml

HMGA2 (high mobility group A2) 高遷移率族蛋白A2抗原 0.5mg

hnRNP F 英文名稱： 異質(zhì)核糖核蛋白F抗體 0.2ml

Rhesus antibody Rh SNX1/Sorting nexin1 分選連接蛋白1抗體 規(guī)格 0.2ml

Anti-JAK1/FITC 熒光素標(biāo)記蛋白質(zhì)酪氨酸激酶JAK-1抗體IgGMulti-class antibodies規(guī)格： 0.2ml

CA19-9(Human Carbohydrate antigen19-9) ELISA Kit 人糖鏈抗原19-9Multi-class antibodies規(guī)格： 48T

Anti-PKC beta 1/2 蛋白激酶C beta 1/2抗體Multi-class antibodies規(guī)格： 0.1ml

Rhesus antibody Rh HIF3 alpha 缺氧誘導(dǎo)因子3α/HIF-3α抗體 規(guī)格 0.1ml

TSST-1(Mouse toxic shock syndrome toxin) ELISA Kit 小鼠毒性休克綜合征毒素1 96T

PELO 英文名稱： PELO蛋白抗體 0.2ml

Troponin T 英文名稱： 心肌特異性肌鈣蛋白T抗體 0.1ml

Anti-PKC beta 1/2 蛋白激酶C beta 1/2抗體Multi-class antibodies規(guī)格： 0.1ml

u-T3(Human Ultrasensitivity Tri-iodothyronine) ELISA Kit 人高敏三碘甲狀腺原氨酸Multi-class antibodies規(guī)格： 48T

Anti-LH 促黃體生成素單克隆抗體Multi-class antibodies規(guī)格： 0.1ml

Rhesus antibody Rh KLK6 激肽釋放酶6抗體 規(guī)格 0.2ml

PDGFsR- Alpha ELISA Kit 大鼠血小板衍生生長因子可溶性受體α 96T

phospho-PYK2 (Tyr402) 英文名稱： 磷酸化富含脯酸的酪酸激酶2抗體 0.1ml

CAB39L 英文名稱： 鈣結(jié)合蛋白樣39抗體 0.2ml

Anti-LH 促黃體生成素單克隆抗體Multi-class antibodies規(guī)格： 0.1ml

CM-H011人完全培養(yǎng)基100mL

CD55 Others Mouse 小鼠 CD55 / DAF 人細(xì)胞裂解液 (陽性對照)

胰蛋白酶-EDTA(含100mL酶解緩沖液) 10mL

TT人甲狀腺導(dǎo)管癌細(xì)胞 TT human thyroid duct carcinoma cells F-12K+10%FBS

IL21 Protein Canine 重組狗 IL21 / Ierleukin 21 蛋白

人表皮黑色素細(xì)胞-中色素(HEM)( 5×105 ) MN-c, 小鼠皮質(zhì)神經(jīng)元 Mouse

CM-H008人氣管上皮細(xì)胞完全培養(yǎng)基100mL

ADAM17 Others Rat 大鼠 ADAM17 人細(xì)胞裂解液 (陽性對照)

原代神經(jīng)膠質(zhì)細(xì)胞特制基礎(chǔ)培養(yǎng)基Many types of cells包裝：500/250/100ml

6T-CEM細(xì)胞，人T細(xì)胞細(xì)胞 綠色熒光蛋白標(biāo)記小鼠子細(xì)胞,U14-GFP細(xì)胞 前脂肪細(xì)胞分化培養(yǎng)基PADM-prf

NCI-H1703(人肺鱗癌細(xì)胞) 5×106cells/瓶×2

BHK-21(倉鼠腎細(xì)胞) 5×106cells/瓶×2 CM-M022小鼠甲狀腺上皮細(xì)胞完全培養(yǎng)基100mL 人B細(xì)胞;RAMOS

蛋白酶體PSMD3抗體規(guī)格 STX8 Others Human 人 STX8 / Syaxin 8 人細(xì)胞裂解液 (陽性對照)

胃粘膜上皮細(xì)胞Many types of cells包裝：5 × 105次方(1ml)

大鼠肝細(xì)胞;BRL

PG-LH7細(xì)胞，人肺巨細(xì)胞癌(PG)的低轉(zhuǎn)移亞系 小鼠胚成纖維包裝細(xì)胞,ψ2細(xì)胞 CL-0026ARPE-19(人視網(wǎng)膜上皮細(xì)胞)5×106cells/瓶×2

ST(豬細(xì)胞) 5×106cells/瓶×2

HDMEC-c pre-screened 人真皮微內(nèi)皮細(xì)胞(HDMEC)預(yù)選型 500,000cells 肝實(shí)質(zhì)細(xì)胞Many types of cells包裝：5 × 105次方(1ml)

技術(shù)外包服務(wù):

★蛋白酶體PSMD3抗體規(guī)格 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測序、載體構(gòu)建等

★蛋白工程：原核、哺乳動物蛋白表達(dá)系統(tǒng)等

★病毒包裝：腺病毒、慢病毒等

★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★細(xì)胞工程：細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。