中文名稱  凋亡相關(guān)蛋白10抗體規(guī)格 

英文名稱  Anti-PDCD10

別    名 Apoptosis related protein 15; CCM3; Cerebral cavernous malformations 3 protein; MGC1212; MGC24477; PDC10_HUMAN; PDCD 10; PDCD10; Programmed cell death 10; Programmed cell death protein 10; TF 1 cell apoptosis related protein 15; TF-1 cell apoptosis-related protein 15; TFAR15.

產(chǎn)品屬性：

凋亡相關(guān)蛋白10抗體規(guī)格 濃    度  1mg/1ml

規(guī) 格  0.2ml/200μg

抗體來(lái)源  Rabbit

克隆類型   polyclonal

交叉反應(yīng)   Human, Mouse, Rat, Chicken, Pig, Horse, Rabbit

產(chǎn)品類型   一抗  

研究領(lǐng)域    細(xì)胞生物 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 細(xì)胞凋亡 激酶和磷酸酶

蛋白分子量  predicted molecular weight: 22kDa 

性    狀   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from humna PDCD10

亞    型  IgG

純化方法   affinity purified by Protein A

儲(chǔ) 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

凋亡相關(guān)蛋白10抗體規(guī)格 產(chǎn)品應(yīng)用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蠟切片需做抗原修復(fù)） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].

Function : Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and MST4 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development.

Subunit : Homodimer. Interacts (via C-terminus) with CCM2 and PXN. Interacts (via N-terminus) with MST4, STK24 and STK25. Interacts with GOLGA2. Identified in a complex with CCM1 and CCM2. Interacts with KDR/VEGFR2. Interaction with KDR/VEGFR2 is enhanced by stimulation with VEGFA.

Subcellular Location : Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Partially co-localizes with endogenous PXN at the leading edges of migrating cells.

DISEASE : Defects in PDCD10 are the cause of cerebral cavernous malformations type 3 (CCM3) [MIM:603285]. Cerebral cavernous malformations (CCMs) are congenital vascular anomalies of the central nervous system that can result in hemorrhagic stroke, seizures, recurrent headaches, and focal neurologic deficits. CCMs have an incidence of 0.1%-0.5% in the general population and usually present clinically during the 3rd to 5th decade of life. The lesions are characterized by grossly enlarged blood vessels consisting of a single layer of endothelium and without any intervening neural tissue, ranging in diameter from a few millimeters to several centimeters.

Similarity : Belongs to the PDCD10 family.

Database links : UniProtKB/Swiss-Prot: Q9BUL8.1

實(shí)驗(yàn)流程：

全、新、優(yōu)、品、好四大特點(diǎn)：

凋亡相關(guān)蛋白10抗體規(guī)格 全：公司提供上萬(wàn)種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標(biāo)準(zhǔn)品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細(xì)胞等，基本上各種科研所需產(chǎn)品在我司都能找到。

新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。

優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。

好：我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊(duì)，產(chǎn)品一旦售出，實(shí)驗(yàn)過(guò)程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時(shí)沒(méi)有任何的后顧之憂。

技術(shù)外包服務(wù):

★凋亡相關(guān)蛋白10抗體規(guī)格 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測(cè)序、載體構(gòu)建等

★蛋白工程：原核、哺乳動(dòng)物蛋白表達(dá)系統(tǒng)等

★病毒包裝：腺病毒、慢病毒等

★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★細(xì)胞工程：細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。

正在熱銷的相關(guān)產(chǎn)品：

28S rRNP(Human 28S ribosome RNP antibody) ELISA Kit 人28S抗核糖體抗體Multi-class antibodies規(guī)格： 48T

Anti-IL-12 (rat, mouse) 白介素12抗體 (大鼠，小鼠)Multi-class antibodies規(guī)格： 0.1ml

Rhesus antibody Rh Mad2L1 有絲分裂阻滯缺陷2樣蛋白1抗體 規(guī)格 0.2ml

CETP(Human glial fibrillary acidic protein) ELISA Kit 人膽固醇酯轉(zhuǎn)移蛋白 96T

RRM1 英文名稱： 核糖核苷酸還原酶1抗體 0.1ml

Transferrin receptor 英文名稱： 轉(zhuǎn)鐵蛋白受體抗體 0.1ml

Anti-IL-12 (rat, mouse) 白介素12抗體 (大鼠，小鼠)Multi-class antibodies規(guī)格： 0.1ml

PRL(mouse prolactin) ELISA Kit 小鼠催乳素Multi-class antibodies規(guī)格： 48T

Anti-CD59/FITC 熒光素標(biāo)記反應(yīng)性溶血膜抑制蛋白抗體IgGMulti-class antibodies規(guī)格： 0.2ml

Rhesus antibody Rh DPV(Duck plague virus) 鴨瘟病毒DPV抗體 規(guī)格 0.2ml

MHB(Rat Methemoglobin,MHB) ELISA Kit 大鼠高鐵血紅蛋白 96T

MAP1A 英文名稱： 微管相關(guān)蛋白1A抗體 0.1ml

Phospho-AP2M1 (Thr156) 英文名稱： 磷酸化接頭相關(guān)蛋白復(fù)合體AP-2μ鏈1抗體 0.1ml

Anti-CD59/FITC 熒光素標(biāo)記反應(yīng)性溶血膜抑制蛋白抗體IgGMulti-class antibodies規(guī)格： 0.2ml

Anti-GST-Tag/HRP 辣根過(guò)氧化物酶標(biāo)記兔抗重組谷胱甘肽轉(zhuǎn)移酶GST標(biāo)簽蛋白抗體IgGMulti-class antibodies規(guī)格： 0.2ml

Anti-Pan-ras/FITC 熒光素標(biāo)記抗Pan ras抗體IgGMulti-class antibodies規(guī)格： 0.2ml

Rhesus antibody Rh BCL2L12 BCL2樣12含脯氨酸蛋白抗體 規(guī)格 0.2ml

ABL1(v-abl Abelson murine leukemia viral oncogene homolog 1) ABL1抗原 0.5mg

GBP7 英文名稱： G蛋白結(jié)合蛋白7抗體 0.2ml

Rhesus antibody Rh Rabbit Anti-rat IgM/RBITC 羅丹明標(biāo)記的兔抗大鼠IgM 規(guī)格 0.3ml

Anti-Pan-ras/FITC 熒光素標(biāo)記抗Pan ras抗體IgGMulti-class antibodies規(guī)格： 0.2ml

大鼠基質(zhì)金屬蛋白酶9/明膠酶B(MMP-9/Gelatinase B) ELISA 試劑盒 96T/48T 試劑盒 組裝/原裝

人親環(huán)蛋白A(PPIA/CYPA)免疫試劑盒 Human cyclophilin A,PPIA/CYPA ELISA Kit

Mousemalondialchehyche,MDAELISAKit小鼠二(MDA)ELISA試劑盒規(guī)格：96T/48T

P16蛋白表達(dá)西方雜交分析試劑盒5次

HumanNuclearmaixprotein22,NMP-22ELISA試劑盒人核基質(zhì)蛋白22(NMP-22)ELISA試劑盒規(guī)格：96T/48T

HumaeceptorⅢfoheFcregionofimmunoglobulinG,FcγRⅢELISAKit人免疫球蛋白GFc段受體Ⅲ(FcγRⅢ/CD16)ELISA試劑盒規(guī)格：96T/48T

大鼠β淀粉樣蛋白1-42(Aβ1-42)ELISA 試劑盒 96T/48T 試劑盒 組裝/原裝

人磷酸烯醇式酸羧激酶(PCK)免疫試劑盒 Human phosphoenolpyruvate carboxykinase,PCK ELISA Kit

PorcineCollageypeⅢ,ColⅢELISAKit豬Ⅲ型膠原(ColⅢ)ELISA試劑盒規(guī)格：96T/48T

石蠟切片組織組蛋白NBT顯色光學(xué)顯微鏡檢測(cè)試劑盒10/20次

Humaotavirusaigen,RVAgELISA試劑盒人輪狀病毒抗原(RVAg)ELISA試劑盒規(guī)格：96T/48T

humanubiquitinD,UBDELISAKit人泛素蛋白D(UBD)ELISA試劑盒規(guī)格：96T/48T

凋亡相關(guān)蛋白10抗體規(guī)格 大鼠白介素8受體β(IL8Rβ)ELISA試劑盒 ，英文名： IL8Rβ ELISA Kit

Human beta 2 microglobulin (BMG/ 2-MG) ELISA Kit 人β2微球蛋白(BMG/β2-MG)ELISA試劑盒

Pla25-DihydroxyvitaminD3,HVD3ELISAKit 植物25羥基維生素D3(25(OH)D3/25HVD3)ELISA試劑盒 96T/48T 進(jìn)口分裝

CLIAKitforCNX(Humancalnexin)ELISAKit人鈣聯(lián)蛋白規(guī)格：48T/96T

細(xì)胞游離膽固醇毛地黃皂苷法(DIGITONIN)高氯酸萘醌(PAN)染色試劑盒50次

Ratc-fosELISAKit大鼠c-fosELISA試劑盒規(guī)格：96T/48T